Results 51 to 60 of about 145,346 (297)
FEBS Open Bio, EarlyView.NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi +6 more
wiley +1 more source
Selçuk Üniversitesi Sosyal Bilimler Meslek Yüksekokulu DergisiInternational Market Selection (IMS) is crucial for companies seeking growth and expansion beyond their domestic boundaries. IMS is a strategic decision that requires careful evaluation of several factors to minimize risks and achieve long-term success ...
Emre Kadir Özekenci
doaj +1 more source
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Exports, Export Destinations, and Skills [PDF]
American Economic Review, 2012 This paper explores the links between exports, export destinations, and skill utilization. We identify two mechanisms behind these links: differences across destinations in quality valuation and in exporting required services, activities that are intensive in skilled labor. Depending on the characteristics of the source country (income, language), the
Irene Brambilla +2 more
openaire +3 more sources
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
FEBS Open Bio, EarlyView.The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Kenya at a Crossroads: Hopes and Fears Concerning the Development of Oil and Gas Reserves
Revue Internationale de Politique de Développement, 2013 Kenya is expected to become a hydrocarbon producer and an oil export hub in the coming years and if properly managed, oil and gas could provide Kenya with a unique opportunity to cement the path towards sustainable economic growth that the country ...
Patricia I. Vasquez
doaj +1 more source
Relationships Between Export Success, Export Strategies, and Export Planning
Journal of Business Strategies, 1970 The remarkable pace of change in world markets has caused a fundamental shiftin the number of possible avenues of growth for U.S. exporters. Eastern Bloc countriesand the republics of the former Soviet Union are actively soliciting trade. Asianeconomies are experiencing growth at an unprecedented rate.
Granger Macy +2 more
openaire +2 more sources
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source