Results 41 to 50 of about 746,135 (367)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Foreign direct investments in the role of strengthening the export competitiveness of the Serbian economy [PDF]

open access: yesEkonomika Poljoprivrede (1979), 2016
The globalization of economic activity imposes the need for all countries to participate intensely in the current international economic cooperation and exchange processes of goods, services, labor and capital.
Đurić Dejan   +2 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Structural problems and prospects of innovative development of economies of countries of the South Caucasus [PDF]

open access: yesMarketing i Menedžment Innovacij, 2013
The aim of the article. The aim of the article is justification of prospects of further innovative development of economies of three countries of the South Caucasus. The results of the analysis. After the collapse of the Soviet Union, the South Caucasus
A.A. Egiazarian
doaj  

COVID‐19 Pandemic Impact on the Exports and Imports

open access: yesRomanian Economic Journal, 2021
This paper’s objectives are the following: describing the impact of the COVID 19 crisis on the mechanism of export-import operations; the evolution of Romania’s export-import activities during 2020-2021 and identifying some recommendations meant to help ...
Mihaela Gabriela Belu
doaj   +1 more source

Malaysian bilateral exports and bilateral real exchange rates [PDF]

open access: yes, 2007
This paper analyzes the performance of Malaysian bilateral exports to its major importing countries: the United States, Japan, and Singapore and then investigates whether the export performance could be improved through depreciation or devaluation of ...
Yusoff, Mohammed
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Systemic Problems of Ensuring the Competitiveness of Exporters in Foreign Markets [PDF]

open access: yesProblemi Ekonomiki, 2016
The key trends of macroeconomic and macro-financial nature, which influence the formation of competitiveness of domestic exporters, have been identified.
Vlasiuk Taras O.
doaj  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

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