Results 51 to 60 of about 138,882 (313)

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Systemic Problems of Ensuring the Competitiveness of Exporters in Foreign Markets [PDF]

Problemi Ekonomiki, 2016
The key trends of macroeconomic and macro-financial nature, which influence the formation of competitiveness of domestic exporters, have been identified.
Vlasiuk Taras O.
doaj  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Global value chain trade and sanction bypass: evidence from the United States

Frontiers in Political Science
Global value chains and trade in intermediates have been proposed as one of the most important systemic changes in the global economic order. Besides their implication for the international trade, investment, and growth, we propose that they also have ...
Aydin B. Yildirim, J. Tyson Chatagnier
doaj   +1 more source

Problems of export orientation of Ukrainian industrial enterprises [PDF]

Marketing i Menedžment Innovacij, 2016
The aim of the article.The purpose of the article is to study the current state of foreign trade in building materials and to identify the main barriers limiting exports in this area. The results of the analysis.
V.V. Smachylo, V.Yu. Khalina
doaj  

Latvia Exports, 1919-1939

, 2022
This dataset contains data on Latvia exports by exports categories (Latvian lats, LVL) and Latvia exports structure by exports categories (%) in 1919-1939.
Markevičiūtė, Jurgita, Ambrulevičiūtė, Aelita, Morkevičius, Vaidas, Žvaliauskas, Giedrius, Norkus, Zenonas   +4 more
core  

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

ROMANIAN FOOTWEAR INDUSTRY -EVOLUTIONS AND CHARACTERISTICS [PDF]

Analele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2014
Footwear industry represents an important sector in national economy. Most of its production goes to export, Romania being the 14th footwear exporter worldwide.
OFILEANU DIMI
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