Results 31 to 40 of about 38,621 (267)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Competitive advantages and composition of the trade balance between Brazil and Argentina: an analysis of indicators of foreign trade

open access: yesEconomia & Região, 2021
This work aims to analyze the commercial relations between Brazil and Argentina in the years 2000, 2005, 2010, 2015 and 2019, through the use of foreign trade indicators such as Degree of Openness, Comparative Advantage Revealed, Revealed Symmetric ...
Carolina Araújo Sousa   +2 more
doaj   +1 more source

Logistics and exports [PDF]

open access: yes, 2008
Drawing on a new and comprehensive measure of logistics quality, our gravity model suggests logistics in the exporting and partner-country can have an important impact on bilateral exports. A one standard deviation improvement in the exporter’s logistics quality, which for example would improve Gabon to the level of Guinea, would raise exports by ...
Alberto Behar, Phil Manners
openaire   +3 more sources

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Paratuberculosis in small ruminants in the Sudan: prevalence and risk factors

open access: yesBMC Veterinary Research
Background Paratuberculosis (PTB), caused by Mycobacterium avium subsp. paratuberculosis (MAP), is a contagious and chronic enteric disease of ruminants and many non-ruminants leading to emaciation and death of the animal.
Sanaa M. Idris   +12 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Delineating the role of rhizospheric microbes in the amelioration of hexavalent chromium stress in plants

open access: yesSustainable Chemistry for the Environment
Hexavalent Chromium is mostly formed from various mining and industrial activities and has severe toxic implications for biotic components. It also hampers soil nutrient profile, thus hindering plant productivity.
Satyabrata Nanda   +2 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Much ado about… everything: The plight of Southern European economies from a national competitiveness perspective

open access: yesJournal of Global Business Insights, 2016
This paper identifies what are understood to be key drivers of country competitiveness. These are the institutional and structural conditions in an economy that are linked with the attainment of sustainable national competitive advantages through the ...
Rui Da Silva, Natalia Teixeira
doaj   +1 more source

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