Results 131 to 140 of about 17,412 (233)

Advancing translational exposomics: bridging genome, exposome and personalized medicine

Human Genomics
Abstract Understanding the interplay between genetic predisposition and environmental and lifestyle exposures is essential for advancing precision medicine and public health. The exposome, defined as the sum of all environmental exposures an individual encounters throughout their lifetime, complements genomic data by elucidating how external ...
Sarigiannis, Dimosthenis, Karakitsios, Spyros, Anesti, Ourania, Stem, Arthur, Valvi, Damaskini, Sumner, Susan C.J., Chatzi, Leda, Snyder, Michael P., Thompson, David C., Vasiliou, Vasilis   +9 more
openaire   +3 more sources

The Exposome and the Kidney: A Silent Dialogue Shaping Chronic Kidney Disease

Journal of Xenobiotics
Genetic predisposition accounts for less than 20% of the global disease burden, highlighting the substantial role of environmental factors in health outcomes.
Livia Alvarenga, Marcia Ribeiro, Ludmila F. M. F. Cardozo, Natália A. Borges, Peter Stenvinkel, Denise Mafra   +5 more
doaj   +1 more source

Reversibility of Age-related Oxidized Free NADH Redox States in Alzheimer's Disease Neurons by Imposed External Cys/CySS Redox Shifts. [PDF]

, 2019
Redox systems including extracellular cysteine/cystine (Cys/CySS), intracellular glutathione/oxidized glutathione (GSH/GSSG) and nicotinamide adenine dinucleotide reduced/oxidized forms (NADH/NAD+) are critical for maintaining redox homeostasis. Aging as
Brewer, Gregory J, Digman, Michelle A, Dong, Yue, Sameni, Sara   +3 more
core  

Holistic evaluation of the impact of pregnancy urban exposome on infant wheezing and chest infections: an outcome-wide approach

Environment International
Background: Few studies have considered the complex interplay of the urban exposome in association with multiple respiratory outcomes during infancy. Aim: Utilizing an outcome-wide exposome approach, we aimed to assess associations of pregnancy urban ...
Robin M. Sinsamala, Augusto Anguita-Ruiz, Xavier Basagaña, Maria Foraster, Mireia Gascon, Elisa Llurba, Chongliang Luo, Mark J. Nieuwenhuijsen, Cecília Persavento, Ioar Rivas, Yu Zhao, María Dolores Gómez-Roig, Jordi Sunyer, Alessandro Marcon, Ane Johannessen, Payam Dadvand   +15 more
doaj   +1 more source

Plaque Psoriasis Exacerbation and COVID-19 Vaccination: Assessing the Characteristics of the Flare and the Exposome Parameters

Vaccines
The diverse patient population and widespread vaccination in the COVD-19 era make vaccine-triggered episodes of psoriasis an ideal model of exposome research.
Emmanouil Karampinis, Myrto-Maria Papadopoulou, Kleoniki Chaidaki, Konstantina-Eirini Georgopoulou, Stavroula Magaliou, Angeliki Viktoria Roussaki Schulze, Dimitrios P. Bogdanos, Efterpi Zafiriou   +7 more
doaj   +1 more source

The implications of healthcare professionals wearing jewelry on patient care biosafety: observational insights and experimental approaches

Scientific Reports
The use of jewelry among healthcare professionals poses a risk of cross contamination due to potential bacterial accumulation and spread. Through a mixed-method design, this study first analyzed the implications of healthcare professionals wearing ...
Isabela Fernanda Larios Fracarolli, Evandro Watanabe, Viviane de Cássia Oliveira, Marinila Buzanelo Machado, Felipe Lazarini Bim, Lucas Lazarini Bim, Denise de Andrade, Maria Helena Palucci Marziale   +7 more
doaj   +1 more source

Meet-in-the-middle meets multi-omics identifying molecular signatures of environmental drivers of childhood overweight

Environment International
Background: Obesity is a multi-cause chronic disease recognized across the lifespan, with childhood obesity prevalence rising over the past decades. Although exposome-wide association studies have identified early-life environmental drivers of child ...
Congrong Wang, Brigitte Reimann, Tim S Nawrot, Dries S Martens, John Wright, Rosemary McEachan, Johanna Lepeule, Wenlun Yuan, Leda Chatzi, Marina Vafeiadi, Regina Grazuleviciene, Sandra Andrusaityte, Oliver Robinson, Jordi Sunyer, Hector Keun, Chung-Ho E. Lau, Alexandros P. Siskos, Muireann Coen, Eva Borràs, Eduard Sabidó, Juan R. González, Marta Vives-Usano, Xavier Estivill, Angel Carracedo, Carlos Ruiz-Arenas, Inés Quintela, Maribel Casas, Mark Nieuwenhuijsen, Ibon Tamayo, Kristine B Gutzkow, Cathrine Thomsen, Amrit K. Sakhi, Mariona Bustamante, Lea Maitre, Martine Vrijheid, Michelle Plusquin, Rossella Alfano   +36 more
doaj   +1 more source

Redefining skin toxicity in the age of precision immunotherapy

Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 5, Page 716-717, May 2026.
Florentia Dimitriou, Christian Posch
wiley   +1 more source

Adolescent idiopathic scoliosis (AIS), environment, exposome and epigenetics: a molecular perspective of postnatal normal spinal growth and the etiopathogenesis of AIS with consideration of a network approach and possible implications for medical therapy [PDF]

, 2011
R Geoffrey Burwell, Peter H Dangerfield, Alan Moulton, Theodoros B Grivas   +3 more
core   +1 more source

Only one health, and so many omics [PDF]

, 2015

core   +1 more source