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Current Environmental Health Reports, 2015 The exposome concept takes a holistic approach facilitated by new and emerging technologies to describe 'the totality of human environmental (i.e. non-genetic) exposures from conception onwards, complementing the genome'. It provides a framework to advance the environmental epidemiology field that has until now focused almost exclusively on single ...
Oliver Robinson, Martine Vrijheid
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The Exposome: Molecules to Populations
Annual Review of Pharmacology and Toxicology, 2019 Derived from the term exposure, the exposome is an omic-scale characterization of the nongenetic drivers of health and disease. With the genome, it defines the phenome of an individual. The measurement of complex environmental factors that exert pressure on our health has not kept pace with genomics and historically has not provided a similar level of ...
Megan M Niedzwiecki +2 more
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Clinics in Chest Medicine, 2019
This article on exposome and asthma focuses on the interaction of patients and their environments in various parts of their growth, development, and stages of life. Indoor and outdoor environments play a role in pathogenesis via levels and duration of exposure, with genetic susceptibility as a crucial factor that alters the initiation and trajectory of
Ahila, Subramanian, Sumita B, Khatri
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This article on exposome and asthma focuses on the interaction of patients and their environments in various parts of their growth, development, and stages of life. Indoor and outdoor environments play a role in pathogenesis via levels and duration of exposure, with genetic susceptibility as a crucial factor that alters the initiation and trajectory of
Ahila, Subramanian, Sumita B, Khatri
openaire +2 more sources
The exposome in rheumatoid arthritis
Joint Bone Spine, 2022The exposome integrates the variety and accumulation of exposures (external and internal) to which an individual is submitted to from conception to death. Exposome may therefore be a useful tool for understanding the diversity of these factors and their role in the pathophysiology of rheumatoid arthritis (RA).
Jerome, Biton +5 more
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