Results 71 to 80 of about 5,008,834 (310)
Environmental Exposure, Biomonitoring and Exposure Assessment
Environmental exposure plays an important role in the development of diseases. However, individuals are exposed to complex mixtures of substances (e.g., chemicals, pollution, and diet) that change throughout a person’s life.
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Ethnic differences in patterns of occupational exposure in New Zealand.
, 2011 OBJECTIVES: To investigate the differences in occupational exposure between Māori (New Zealand's indigenous people) and non-Māori. METHODS: Participants were randomly selected from the Electoral Roll.
Andrea 't Mannetje +11 more
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Sex differences in noradrenergic regulation of the medial prefrontal cortex in mice
Biology of Sex DifferencesBackground Norepinephrine (noradrenaline; NE) is a stress signal released from the locus coeruleus (LC) into the prefrontal cortex (PFC) to govern arousal, attention, and cognition.
Marcis V. Scroger +12 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Lead Exposure and Prevention Advisory Committee (LEPAC) : 2020 annual report to U.S. Department of Health and Human Services [PDF]
The objective of the Lead Exposure and Prevention Advisory Committee (LEPAC) is to review research andFederal programs and services related to lead poisoning and to identify effective services and best practices for addressing and preventing lead ...
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Mapping efforts to identify populations at higher risk of lead exposure: HUD perspective [PDF]
HUD-mapping-efforts-populations-high-risk-lead-exposure-Dec-LEPAC-508 ...
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, 2022 With the recent improvements in high-resolution mass spectrometry (HRMS), retrospective chemical analysis has been increasingly used in environmental sciences.
Dubocq, Florian +3 more
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Lead Exposure and Prevention Advisory Committee (LEPAC) : 2021 annual report to U.S. Department of Health and Human Services [PDF]
The objective of the Lead Exposure and Prevention Advisory Committee (LEPAC) is to review research and federal programs and services related to lead poisoning and to identify effective services and best practices for addressing and preventing lead ...
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