Results 91 to 100 of about 5,008,834 (310)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
In this paper we examine the relationship between exchange rate movements and firm value. We estimate the exchange rate exposure of publicly listed firms in a sample of eight (non-US) industrialized and emerging markets, and find that a significant ...
Kathryn M.E. Dominguez, Linda L. Tesar
core
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Lead Exposure and Prevention Advisory Committee (LEPAC) meeting : National Center for Environmental Health (NCEH), Centers for Disease Control and Prevention (CDC), December 3, 2021, 9:00 a.m. ET to 4:05 p.m. ET : meeting summary [PDF]
The Lead Exposure and Prevention Advisory Committee (LEPAC) convened on December 3, 2021. Remote participation through a virtual ZOOM meeting was used to hold the meeting.
core
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Risk management for waterborne pathogens in public swimming pools: A pilot study
There have been numerous reports of swimming pool-associated outbreaks of Cryptosporidiosis and Giardiasis worldwide, including Australia. It is essential to ensure that effective measures are in place to manage faecal contamination incidents, the ...
McManus, Alexandra +4 more
core
Retrospective Surveillance of Wastewater To Examine Seasonal Dynamics of Enterovirus Infections
Enteroviruses are RNA viruses that are responsible for both mild gastroenteritis and mild respiratory illnesses as well as debilitating diseases such as meningitis and myocarditis.
Nichole E. Brinkman +2 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
The problems of the overwhelming amount of medical literature have been thoughtfully highlighted in the PLoS Medicine editorial “Drowning or Thirsting: The Extremes of Availability of Medical Information” [ 1]. It is of vital importance to medical professionals that they improve on their skills of sifting through the huge amounts of literature that are
openaire +3 more sources

