Results 111 to 120 of about 5,008,834 (310)

Investigating the relationship between nature exposure, nature connectedness and wellbeing in individuals with cancer

Prior quantitative research has highlighted the benefits that nature brings to the well-being of cancer survivors. Here, an Interpretative phenomenological analysis was adopted to investigate the relationship between nature exposure, nature connectedness
Haughton, Melanie, Kotera, Yasuhiro, Quah, A, Quah, Amanda, Haughton, M., Kotera, Y.   +5 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Building a European exposure science strategy

, 2019
Exposure information is a critical element in various regulatory and non-regulatory frameworks in Europe and elsewhere. Exposure science supports to ensure safe environments, reduce human health risks, and foster a sustainable future. However, increasing
Otto Hänninen, André Conrad, Ahrens, Andreas, Zare Jeddi, Maryam, Gerhard Heinemeyer, Conrad, André, Jelle Vlaanderen, Vermeire, Theo, Andreas Ahrens, Bessems, Jos, Stylianos Kephalopoulos, Coggins, Marie A, Susana Viegas, Alison Connolly, von Goetz, Natalie, Rother, Dag, Natalie von Goetz, Bruinen de Bruin, Yuri, Maryam Zare Jeddi, Jos Bessems, Coggins, Marie A., Michael McLachlan, Poulsen, Veronique, Vlaanderen, Jelle, Urs Schlüter, Dag Rother, Jim Bridges, Tatsiana Dudzina, Kephalopoulos, Stylianos, Meijster, Tim, McLachlan, Michael, Hänninen, Otto, Veronique Poulsen, Yuri Bruinen de Bruin, Dudzina, Tatsiana, Viegas, Susana, Jeddi, Maryam Zare, Bridges, Jim, Connolly, Alison, Schlüter, Urs, Fantke, Peter, Marie A. Coggins, McLachlan, Michael,, Tim Meijster, Heinemeyer, Gerhard, Peter Fantke, Theo Vermeire   +46 more
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Personal exposure assessment studies may suffer from exposure-relevant selection bias

, 2000
We evaluated exposure-relevant selection bias within the framework of a study on personal air pollution exposure, using traffic data as exposure proxy. Based on random samples of 3000 (Basel) and 2532 (Helsinki) persons, 50 and 250 subjects, respectively,
Rotko, Tuulia, Krütli, Pius, Künzli, Nino, Jantunen, Matti, Kruize, Hanneke, Bayer-Oglesby, Lucy, Boudet, Céline   +6 more
core   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

The Chemical and Products Database v4.0, an updated resource supporting chemical exposure evaluations

Scientific Data
Since the initial release of the Chemical and Products Database (CPDat) in 2018, the United States Environmental Protection Agency has added a considerable amount of chemical exposure-related information to the database and has expanded its schema to ...
Sakshi Handa, Kristin K. Isaacs, Jonathan T. Wall, Allison Larger, Scott Burns, Lauren E. Koval, Kenta Baron-Furuyama, Colleen M. Elonen, David Lyons, Kathie L. Dionisio, M. Beth Horton, Katherine A. Phillips   +11 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Exchange Rate Pegs and Foreign Exchange Exposure in East Asia [PDF]

This paper shows that many East Asian firms are significantly exposed to foreign exchange risk. Their exposure appears to be much more widespread than is typical for the large, western industrialized economies.
David Parsley Helen Popper
core  

A Re-Examination of Exchange Rate Exposure [PDF]

Finance theory suggests that changes in exchange rates should have little influence on asset prices in a world with integrated capital markets. Indeed, the existing literature examining the relationship between international stock prices and exchange ...
Kathryn M.E Dominguez, Linda L. Tesar
core   +2 more sources