Results 161 to 170 of about 2,947,426 (294)

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Evaluation of Exposure Assessment Methods and Procedures for Induction Hobs. [PDF]

Bioelectromagnetics
Xi J, Kühn S, Fortunato C, Ofli E, Kuster N.   +4 more
europepmc   +1 more source

Assessment of field exposure by electronic article surveillance systems [PDF]

, 2011
Goeminne, Francis, Joseph, Wout, Martens, Luc, Verloock, Leen, Vermeeren, Günter   +4 more
core  

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Improving the design of epidemiology studies that use biomonitoring for exposure assessment: a SciPinion panel recommendation. [PDF]

BMC Med Res Methodol
Burstyn I, Cox LA, Cao Y, Eslick G, Harris S, Kheifets L, Kramer M, Langlois P, Lee P, Reiss B, Voortman T, Carneal TM, Hays SM.   +12 more
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Simultaneous Determination of Bisphenol A and Its Analogues in Food Matrixes: Cumulative Exposure Assessment Following New Regulatory Restrictions-A Systematic Review. [PDF]

Foods
Lovrincevic Pavlovic N, Miskulin I, Kotromanovic Simic I, Dumic L, Kotromanovic D, Miskulin M.   +5 more
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Exposure Assessment of Tropane Alkaloids via Barley Grain-Based Products Among Serbian Population. [PDF]

Foods
Stojanović T, Konstantinović B, Bursić V, Vuković G, Milešević J, Zeković M, Šarac I, Pejin Đ, Mandić N, Popov M, Agarski M, Ćurčić M.   +11 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source