Results 161 to 170 of about 7,091,564 (299)

Lead Exposure and Prevention Advisory Committee (LEPAC) : 2020 annual report to U.S. Department of Health and Human Services [PDF]

The objective of the Lead Exposure and Prevention Advisory Committee (LEPAC) is to review research andFederal programs and services related to lead poisoning and to identify effective services and best practices for addressing and preventing lead ...

core  

Generic formulations: availability and applicability for exposure assessment. [PDF]

J Expo Sci Environ Epidemiol
Zaleski RT, Ahrens A, Becker RA, Isaacs K, Phillips K.   +4 more
europepmc   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Impact of sample mass on the reliability of toenail fluoride for exposure assessment. [PDF]

Toxicol Environ Health Sci
Tamayo-Cabeza G, Zenni M, Castiblanco-Rubio GA, Lippert F, Flora DB, Peacock JL, Till C, Goodman CV, Lanphear BP, Korrick SA, Karagas MR, Martinez-Mier EA.   +11 more
europepmc   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Advancing Long-Term Outdoor Air Pollution Exposure Assessment for Health Studies: Lessons from a Multinational Research Initiative. [PDF]

Curr Environ Health Rep
Boogaard H, Crouse DL, Patton AP, Mantus E, Breitner-Busch S, Hart JE, Oudin A, Yang S, Yanosky JD, Volckens J, Milford JB.   +10 more
europepmc   +1 more source

Assessing Exposures [PDF]

, 2018
Parkkinen, V-P., Wallmann, C., Wilde, M., Clarke, B., Illari, P., Kelly, M.P., Norell, C., Russo, Federica, Shaw, B., Williamson, J.   +9 more
openaire   +2 more sources

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Mapping efforts to identify populations at higher risk of lead exposure: HUD perspective [PDF]

HUD-mapping-efforts-populations-high-risk-lead-exposure-Dec-LEPAC-508 ...

core  

Workflow-dependent noise peaks and exposure assessment in operating rooms: implications for occupational risk. [PDF]

Ann Work Expo Health
Katran HB, Ocaktan N, Uzun E, Altinkaynak G.   +3 more
europepmc   +1 more source