Results 171 to 180 of about 2,947,426 (294)

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Probabilistic dietary exposure assessment of polycyclic aromatic hydrocarbons (PAHs) and its associated disease burden in Singapore. [PDF]

Sci Rep
Li A, Chen ME, Lim GS, Er B, Liu MH, Sin V, Seow WJ, Ong GY, Ponampalam R, Tan BKK, Khoo J, Chan JSH, Aung KT.   +12 more
europepmc   +1 more source

Accurate assessment of WLAN exposure in a wireless sensor testbed [PDF]

, 2010
Joseph, Wout, Martens, Luc, Verloock, Leen, Vermeeren, Günter   +3 more
core  

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Simultaneous Quantification of Fumonisins and Their Hydrolyzed Metabolites in Donkey Matrices: A Tool for Exposure Assessment and Toxicokinetic Studies. [PDF]

Toxins (Basel)
Tian D, Zheng Y, Li Y, Xing Q, Lin G, Zhu R, Ma Q, Wang P, Wang R.   +8 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Arsenic, Cadmium, and Lead in Soils and Cereal Grains of the Pannonian Plain (Croatia): Soil-to-Grain Transfer and Dietary Exposure Assessment. [PDF]

Foods
Brkić D, Marinić J, Tomić Linšak D, Jurak G, Lasić D, Bošnir J, Broznić D.   +6 more
europepmc   +1 more source

Interpolation in between road measurements in RF-EMF exposure assessment [PDF]

, 2015
Aerts, Sam, Bolte, John, Colussi, Loek, Joseph, Wout, Kamer, Jos, Martens, Luc   +5 more
core   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Inorganic Arsenic in Rice-Based Beverages: Occurrence in Products Available on the Italian Market and Dietary Exposure Assessment. [PDF]

Foods
D'Amato M, Turco AC, D'Amore T, Vitale F, Marini F, Stacchini P, Sorbo A.   +6 more
europepmc   +1 more source