Results 1 to 10 of about 849,895 (118)

Corticolimbic Circuitry in Chronic Pain Tracks Pain Intensity Relief Following Exposure In Vivo [PDF]

Biological Psychiatry Global Open Science, 2021
Background: A subset of patients with chronic pain who receive exposure in vivo (EXP) treatment experience clinically relevant relief of pain intensity. Although pain relief is not an explicit therapeutic target, it is important to understand how and why
Inge Timmers, Vincent G. van de Ven, Johan W.S. Vlaeyen, Rob J.E.M. Smeets, Jeanine A. Verbunt, Jeroen R. de Jong, Amanda L. Kaas   +6 more
doaj   +2 more sources

Exposure of PM2.5 Exacerbates COVID-19 In Vivo [PDF]

SHS Web of Conferences, 2022
Coronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) affects many tissues and organs, especially lung damage.
Wang Andrew Pindi
doaj   +1 more source

Depolarization shift in the resting membrane potential of inferior colliculus neurons explains their hyperactivity induced by an acoustic trauma

Frontiers in Neuroscience, 2023
IntroductionNeuronal hyperactivity has been associated with many brain diseases. In the auditory system, hyperactivity has been linked to hyperacusis and tinnitus. Previous research demonstrated the development of hyperactivity in inferior colliculus (IC)
Chun-Jen Hsiao, Alexander V. Galazyuk
doaj   +1 more source

Selecting an anti-malarial clinical candidate from two potent dihydroisoquinolones

Malaria Journal, 2021
Background The ongoing global malaria eradication campaign requires development of potent, safe, and cost-effective drugs lacking cross-resistance with existing chemotherapies.
Yizhe Chen, Fangyi Zhu, Jared Hammill, Gloria Holbrook, Lei Yang, Burgess Freeman, Karen L. White, David M. Shackleford, Kathleen G. O’Loughlin, Susan A. Charman, Jon C. Mirsalis, R. Kiplin Guy   +11 more
doaj   +1 more source

Effective population monitoring for determination of the thyroidal radioiodine content of the public following a nuclear accident in Japan

Environmental Advances, 2022
After a nuclear accident, population monitoring is necessary to determine the radiation exposure levels of the affected population. One of the monitoring components is direct thyroid measurements to assess the internal thyroid dose (mainly from 131I with
Osamu Kurihara, Eunjoo Kim, Kotaro Tani, Masumi Ogawa, Kazuaki Yajima, Munehiko Kowatari, Hideo Tatsuzaki   +6 more
doaj   +1 more source

Pain-related fear in adolescents with chronic musculoskeletal pain: process evaluation of an interdisciplinary graded exposure program

BMC Health Services Research, 2020
Background For studying the effectiveness of treatment, it is important to check whether a new treatment is performed as originally described in the study-protocol.
C. Dekker, J. C. M. van Haastregt, J. A. M. C. F. Verbunt, J. R. de Jong, T. van Meulenbroek, H. F. M. Pernot, A. D. van Velzen, C. H. G. Bastiaenen, M. E. J. B. Goossens   +8 more
doaj   +1 more source

Exposure in vivo Induced Changes in Neural Circuitry for Pain-Related Fear: A Longitudinal fMRI Study in Chronic Low Back Pain

Frontiers in Neuroscience, 2019
Exposure in vivo (EXP) is a cognitive-behavioral treatment aimed at reducing pain-related fear in chronic pain, and has proven successful in reducing pain-related disability in patients with chronic low back pain (cLBP).
Inge Timmers, Inge Timmers, Inge Timmers, Jeroen R. de Jong, Jeroen R. de Jong, Jeroen R. de Jong, Mariëlle Goossens, Mariëlle Goossens, Jeanine A. Verbunt, Jeanine A. Verbunt, Jeanine A. Verbunt, Rob J. Smeets, Rob J. Smeets, Amanda L. Kaas   +13 more
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Exposição ao vivo no tratamento de agorafobia: relato de caso

Psicologia: Ciência e Profissão
Relato de caso, em que a Exposição ao Vivo foi utilizada no tratamento de paciente com diagnóstico de agorafobia. O tratamento foi realizado em doze sessões, apresentando êxito no uso dessa técnica comportamental.
Gustavo J. Fonseca D'El Rey
doaj   +3 more sources

Correlation between the results of in vitro and in vivo chromosomal damage tests in consideration of exposure levels of test chemicals

Genes and Environment, 2018
Introduction We examined the correlation between the results of in vitro and in vivo chromosomal damage tests by using in-house data of 18 pharmaceutical candidates that showed positive results in the in vitro chromosomal aberration or micronucleus test ...
Eiji Yamamura, Chinami Aruga, Shigeharu Muto, Nobuyuki Baba, Yoshifumi Uno   +4 more
doaj   +1 more source

Label-free detection of uptake, accumulation, and translocation of diesel exhaust particles in ex vivo perfused human placenta

Journal of Nanobiotechnology, 2021
Background Pregnant women and developing fetuses comprise a particularly vulnerable population as multiple studies have shown associations between prenatal air pollution exposure and adverse pregnancy outcomes.
Eva Bongaerts, Leonie Aengenheister, Battuja B. Dugershaw, Pius Manser, Maarten B. J. Roeffaers, Marcel Ameloot, Tim S. Nawrot, Hannelore Bové, Tina Buerki-Thurnherr   +8 more
doaj   +1 more source