Results 121 to 130 of about 87,598,632 (299)
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Annual Report - Marine Biological Laboratory, 1909
, 1910 Annual report of the Marine Biological Laboratory in Woods Hole. 1909.
Marine Biological Laboratory (Woods Hole MA)
core
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Annual Report - Marine Biological Laboratory, 1925
, 1926 Annual report of the Marine Biological Laboratory in Woods Hole. 1925.
Marine Biological Laboratory (Woods Hole MA)
core
Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank
FEBS Open Bio, EarlyView.Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer +7 more
wiley +1 more source
[Workers' exposure to selected biological agents in libraries of Upper Silesia].
Medycyna pracy, 2008 The aim of this study was to assess the exposure of library workers to biological agents based on quantitative and qualitative characteristics of airborne and settled dust microflora supplemented with the analysis of dust mite allergens. The bioaerosol sampling was carried out using a 6-stage Andersen impactor.
Agnieszka, Wlazło +6 more
openaire +1 more source
Annual Report - Marine Biological Laboratory, 1940
, 1941 Annual report of the Marine Biological Laboratory in Woods Hole. 1940.
Marine Biological Laboratory (Woods Hole MA)
core
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Annual Report - Marine Biological Laboratory, 1917
, 1918 Annual report of the Marine Biological Laboratory in Woods Hole. 1917.
Marine Biological Laboratory (Woods Hole MA)
core
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source