Results 51 to 60 of about 87,598,632 (299)

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Ethnic differences in patterns of occupational exposure in New Zealand.

open access: yes, 2011
OBJECTIVES: To investigate the differences in occupational exposure between Māori (New Zealand's indigenous people) and non-Māori. METHODS: Participants were randomly selected from the Electoral Roll.
Andrea 't Mannetje   +11 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Examining evidence for a protective occupational exposure limit for inhalable manganese dust below which there are no adverse subclinical nervous system effects [PDF]

open access: yes, 2009
Includes abstract.Includes bibliographical references (leaves 47-52).The aim of this study was to investigate the exposure-response relationship between the concentration of inhalable manganese dust and subclinical nervous system outcomes amongst workers
Williams, Haidee Maxine
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Non-lethal effects of entomopathogenic nematode infection

open access: yesScientific Reports, 2021
Entomopathogenic nematodes are typically considered lethal parasites of insect hosts. Indeed they are employed as such for biological control of insect pests.
Camila C. Filgueiras, Denis S. Willett
doaj   +1 more source

Assesing exposure to biological and chemical agents in small eateries [PDF]

open access: yes, 2011
W artykule omówiono czynniki biologiczne i chemiczne występujące w zakładach gastronomicznych. Przedstawiono również wyniki oceny narażenia zawodowego na stanowiskach pracy uzyskane w ramach prowadzonego w CIOP-PIB zadania z zakresu służb państwowych ...
Zapór, L., Kowalska, J.
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Serum dioxin levels in former New Zealand sawmill workers twenty years after exposure to pentachlorophenol (PCP) ceased.

open access: yes, 2009
From the 1950s to the late 1980s pentachlorophenol (PCP) based anti-sapstain fungicides were widely used in the New Zealand timber industry. Workers involved in treatment, or those handling freshly treated timber, experienced significant PCP exposure ...
Shoemack, Phil   +11 more
core   +1 more source

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