Results 71 to 80 of about 91,875,832 (294)
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
, 2020 OF Journal of Biological Regulators & Homeostatic Agents 375 In conclusion, on the basis of our case, we observed that blood eosinophil measurements in overlapping subjects in the different seasons (with high/low allergen exposure), may lead us to ...
Scalese Marco, Sposato B., Rogliani P.
core
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
FEBS Letters, EarlyView.This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Occupational Exposure to biological agents in wastewater treatment plants
, 2014 Poor risk assessment is one of the emerging issues related with the occupational exposure to biological agents. The principles for the management of biological risks are described in the Directive 2000/54/EC and employers are responsible for ensuring ...
Rosa, Nuno +2 more
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Biological agents in the workplace – risk assessment [PDF]
, 2008 Zgodnie z rozporządzeniem ministra zdrowia w sprawie szkodliwych czynników biologicznych dla zdrowia w środowisku pracy oraz ochrony zdrowia pracowników zawodowo narażonych na te czynniki (Dz.U. nr 81/2005, poz.
Zapór, L., Gołofit-Szymczak, M.
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Exposure of ventilation system cleaning workers to harmful microbiological agents [PDF]
, 2013 Background: Regular inspection of the cleanliness of the ventilation systems, as well as their periodic cleaning and disinfection, if necessary, are the main factors of the proper maintenance of each system.
Gołofit-Szymczak, Małgorzata +5 more
core +1 more source
Knowledge of biosecurity measures among health personnel
Horizonte Médico, 2017 Objective: To determine the level of knowledge of biosecurity measures among the professional personnel of the Hospital Nacional Hipólito Unanue (HNHU), to quantify the workers in groups by different features, and to analytically compare their ...
Jorge A. Ruiz de Somocurcio Bertocchi
doaj +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Review on standardized assessment and monitoring of the biosafety and biosecurity in laboratories
One Health & Risk Management, 2023 Introduction. Biological risks continue to intensify due to globalization and the ongoing emergence and re-emergence of communicable diseases. These factors are among the primary destabilizing elements of biological security and remain a major concern ...
Irina LOZNEANU
doaj