Results 71 to 80 of about 87,598,632 (299)
Occupational Exposure to biological agents in wastewater treatment plants
, 2014 Poor risk assessment is one of the emerging issues related with the occupational exposure to biological agents. The principles for the management of biological risks are described in the Directive 2000/54/EC and employers are responsible for ensuring ...
Rosa, Nuno +2 more
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Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Knowledge of biosecurity measures among health personnel
Horizonte Médico, 2017 Objective: To determine the level of knowledge of biosecurity measures among the professional personnel of the Hospital Nacional Hipólito Unanue (HNHU), to quantify the workers in groups by different features, and to analytically compare their ...
Jorge A. Ruiz de Somocurcio Bertocchi
doaj +1 more source
Division of Select Agents & Toxins : protecting America from dangerous [PDF]
Responsible for regulating the possession, use, and transfer of select agents and the importation of infectious biological agents into the U.S. that could cause disease in humans.CS256096GPublication date from document properties.infographic_dsat.pdfCDC ...
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Review on standardized assessment and monitoring of the biosafety and biosecurity in laboratories
One Health & Risk Management, 2023 Introduction. Biological risks continue to intensify due to globalization and the ongoing emergence and re-emergence of communicable diseases. These factors are among the primary destabilizing elements of biological security and remain a major concern ...
Irina LOZNEANU
doaj
Cogitare Enfermagem, 2008 Pesquisa documental exploratória, realizada em hospital público de Fortaleza em 2005. Objetivos: caracterizar os acidentes de trabalho ocorridos entre profissionais de saúde; analisar a freqüência com que ocorrem acidentes de trabalho com dispositivos ...
Débora Conceição Rodrigues Paulino +2 more
doaj +1 more source
Biological monitoring of occupational exposure to polycyclic aromatic hydrocarbons in prebake smelting [PDF]
, 2010 In 1984, the International Agency for Research on Cancer determined that working in the primary aluminium production process was associated with exposure to certain polycyclic aromatic hydrocarbons (PAHs) that are probably carcinogenic to humans.
Di Corleto, Ross
core +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source