Results 61 to 70 of about 87,598,632 (299)

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Cuidado de Enfermería en el tratamiento depurador de pacientes con hepatitis C en hemodiálisis

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2016
Fundamento: la infección por el virus de la hepatitis C causa morbimortalidad en las unidades de hemodiálisis. Objetivo: implementar acciones para mejorar el cuidado de Enfermería en el tratamiento depurador de pacientes portadores de hepatitis C en ...
Juana Lupe Muñoz Callol, Lucía Álvarez Surit, Inés María Merced Len, Noheridis González Saldívar, Alberto Peña López   +4 more
doaj  

Occupational exposure to contaminated biological material: perceptions and feelings experienced among dental students

Revista de Odontologia da UNESP
INTRODUCTION: Dental students may be a particularly vulnerable group exposed to the risk of acquiring infections through occupational injuries.OBJECTIVE: To investigate the perceptions with regard to their occupational exposure to potentially infectious ...
Camila PINELLI, Luis Felipe Garcia Leal MOUTA   +1 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

USE OF PERSONAL PROTECTIVE EQUIPMENT IN A HOME CARE SERVICE

Cogitare Enfermagem, 2016
A cross-sectional study was conducted at a home care service in the state of São Paulo. The objective of the study was to identify the use of personal protective equipment, safety devices, the disposal of sharp objects, and other factors
Jéssica Fernanda Corrêa Cordeiro, Amanda Pavinski Alves, Elucir Gir, Diego Oliveira Miranda, Silvia Rita Marin da Silva Canini   +4 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Occupational Exposure to Biological Agents in Wastewater Treatment Plants

, 2018
Poor risk assessment is one of the emerging issues related with the occupational exposure to biological agents. The Directive 2000/54/EC lays down the principles for the management of biological risks, however, in order to protect workers, the state of ...
Rosa, Nuno, Pires, Ana Filipa, Cano, Manuela, Aguiar, Fátima   +3 more
core  

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source