Melanoma expression analysis with Big Data technologies [PDF]
Melanoma is a highly immunogenic tumor. Therefore, in recent years physicians have incorporated drugs that alter the immune system into their therapeutic arsenal against this disease, revolutionizing in the treatment of patients in an advanced stage of ...
Aldana-Montes, Jose Francisco +4 more
core +2 more sources
Differential expression analysis with global network adjustment [PDF]
<p>Background: Large-scale chromosomal deletions or other non-specific perturbations of the transcriptome can alter the expression of hundreds or thousands of genes, and it is of biological interest to understand which genes are most profoundly ...
A Antonellis +28 more
core +3 more sources
Analysis Expression of ZIP1 and Caspase-3 Protein in Adenocarsinoma of the Prostate [PDF]
Background: Carcinogenesis of adenocarcinoma of the prostate occurs due to dysregulation of zinc level within the cells. Intracellular zinc molecules influx is regulated by a transporter protein ZIP1, whose non-presence is predicted to inhibit apoptosis,
Kodariah, R. (Ria) +2 more
core +3 more sources
Characterization of the human patatin-like phospholipase familys⃞
Several publications have described biological roles for human patatin-like phospholipases (PNPLAs) in the regulation of adipocyte differentiation. Here, we report on the characterization and expression profiling of 10 human PNPLAs.
Paul A. Wilson +4 more
doaj +1 more source
M-quantile regression analysis of temporal gene expression data [PDF]
In this paper, we explore the use of M-regression and M-quantile coefficients to detect statistical differences between temporal curves that belong to different experimental conditions.
Vinciotti, V, Yu, K
core +1 more source
Digital gene expression analysis of the zebra finch genome [PDF]
Background: In order to understand patterns of adaptation and molecular evolution it is important to quantify both variation in gene expression and nucleotide sequence divergence.
Balakrishnan, C.N. +3 more
core +4 more sources
Calmodulin-binding transcription activators (CAMTAs) are evolutionarily conserved transcription factors and have multi-functions in plant development and stress response.
Qiying Zhou +23 more
doaj +1 more source
A genomic analysis and transcriptomic atlas of gene expression in Psoroptes ovis reveals feeding- and stage-specific patterns of allergen expression [PDF]
Background: Psoroptic mange, caused by infestation with the ectoparasitic mite, Psoroptes ovis, is highly contagious, resulting in intense pruritus and represents a major welfare and economic concern for the livestock industry Worldwide.
Bartley, Kathryn +11 more
core +2 more sources
Partition Decoupling for Multi-gene Analysis of Gene Expression Profiling Data [PDF]
We present the extention and application of a new unsupervised statistical learning technique--the Partition Decoupling Method--to gene expression data.
Braun, Rosemary +3 more
core +5 more sources
A computational study of the Warburg effect identifies metabolic targets inhibiting cancer migration
Over the last decade, the field of cancer metabolism has mainly focused on studying the role of tumorigenic metabolic rewiring in supporting cancer proliferation.
Keren Yizhak +8 more
doaj +1 more source

