Melanoma expression analysis with Big Data technologies [PDF]
Melanoma is a highly immunogenic tumor. Therefore, in recent years physicians have incorporated drugs that alter the immune system into their therapeutic arsenal against this disease, revolutionizing in the treatment of patients in an advanced stage of ...
Aldana-Montes, Jose Francisco +4 more
core +2 more sources
M-quantile regression analysis of temporal gene expression data [PDF]
In this paper, we explore the use of M-regression and M-quantile coefficients to detect statistical differences between temporal curves that belong to different experimental conditions.
Vinciotti, V, Yu, K
core +1 more source
A genomic analysis and transcriptomic atlas of gene expression in Psoroptes ovis reveals feeding- and stage-specific patterns of allergen expression [PDF]
Background: Psoroptic mange, caused by infestation with the ectoparasitic mite, Psoroptes ovis, is highly contagious, resulting in intense pruritus and represents a major welfare and economic concern for the livestock industry Worldwide.
Bartley, Kathryn +11 more
core +2 more sources
Characterization of the human patatin-like phospholipase familys⃞
Several publications have described biological roles for human patatin-like phospholipases (PNPLAs) in the regulation of adipocyte differentiation. Here, we report on the characterization and expression profiling of 10 human PNPLAs.
Paul A. Wilson +4 more
doaj +1 more source
The Association between Vitamin D Receptor Expression and Prolonged Overall Survival in Breast Cancer. [PDF]
Summary In this study, we analyzed vitamin D receptor (VDR) expression and survival in a breast cancer patient cohort of 82 breast cancer patients. Immunohistochemical analysis was possible in 91.5% of the patients (75/82). Staining was evaluated using
Berger U +13 more
core +2 more sources
Trajectory-based differential expression analysis for single-cell sequencing data [PDF]
Trajectory inference has radically enhanced single-cell RNA-seq research by enabling the study of dynamic changes in gene expression. Downstream of trajectory inference, it is vital to discover genes that are (i) associated with the lineages in the ...
Cannoodt, Robrecht +7 more
core +2 more sources
Genome-wide gene expression analysis of anguillid herpesvirus 1 [PDF]
<p>Background: Whereas temporal gene expression in mammalian herpesviruses has been studied extensively, little is known about gene expression in fish herpesviruses.
Davison, A.J. +4 more
core +3 more sources
Sucrose nonfermenting-related protein kinase 1 (SnRK1) is one of the critical serine/threonine protein kinases. It commonly mediates plant growth and development, cross-talks with metabolism processes and physiological responses to biotic or abiotic ...
Qian-lin XIAO +10 more
doaj +1 more source
Microarrays are one of the latest breakthroughs in experimental molecular biology, which allow monitoring of gene expression for tens of thousands of genes in parallel and are already producing huge amounts of valuable data. Analysis and handling of such data is becoming one of the major bottlenecks in the utilization of the technology.
Brazma, Alvis, Vilo, Jaak
openaire +3 more sources
Gene Co-expression Network and Copy Number Variation Analyses Identify Transcription Factors Associated With Multiple Myeloma Progression [PDF]
Multiple myeloma (MM) has two clinical precursor stages of disease: monoclonal gammopathy of undetermined significance (MGUS) and smoldering multiple myeloma (SMM). However, the mechanism of progression is not well understood.
Abu Zaid, Mohammad +7 more
core +5 more sources

