Results 251 to 260 of about 8,341,413 (332)

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Express analysis of DNA photosensitizers

open access: yesNucleic Acids Research, 1991
Vadim V. Demidov   +3 more
openaire   +3 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Evaluation of a strategy for parallel protein phosphorylation and expression analysis [PDF]

open access: yes, 2012
Colaert, Niklaas   +6 more
core   +1 more source

Analysis of the gene expression profile in response to human epididymis protein 4 in epithelial ovarian cancer cells

open access: bronze, 2016
Liancheng Zhu   +9 more
openalex   +2 more sources

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