Results 121 to 130 of about 1,642,960 (338)

Purification tags markedly affect self‐aggregation of CPEB3

FEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito, Yujin Lee, Motoharu Ueno, Naotaka Sekiyama, Masatomo So, Ayako Furukawa, Kenji Sugase   +6 more
wiley   +1 more source

Background and approach to a definition of smart buildings [PDF]

, 2014
There is no possibility of finding a single reference about domotics in the first half of the 20th century. The best known authors and those who have documented this discipline, set its origin in the 1970’s, when the x-10 technology began to be used, but
Ganah, Abdulkadir, García, A., Higuera, O., Jiménez, F. J., Millan, Susana   +4 more
core  

Theory Morphisms in Church's Type Theory with Quotation and Evaluation

, 2017
${\rm CTT}_{\rm qe}$ is a version of Church's type theory with global quotation and evaluation operators that is engineered to reason about the interplay of syntax and semantics and to formalize syntax-based mathematical algorithms. ${\rm CTT}_{\rm uqe}$
J Carette, J Harrison, MJC Gordon, PB Andrews, WM Farmer, WM Farmer, WM Farmer, WM Farmer, WM Farmer, WM Farmer   +9 more
core   +1 more source

Bitcoin in the Scientific Literature – A Bibliometric Study

Studies in Business and Economics, 2019
Since 2012, there has been growing interest in bitcoin scientific research from different fields, including computer science and engineering, economics, business and finance, law and regulatory. The purpose of this paper is to evaluate bitcoin literature
Ramona Orăștean, Cristina Mărginean Silvia, Raluca Sava   +2 more
doaj   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

3D FACIAL LANDMARK-BASED DECEPTION DETECTION IN VIDEO USING GRU MODEL

Mağallaẗ Al-kūfaẗ Al-handasiyyaẗ
Deception detection is an interdisciplinary field that has researchers from psychology, criminology, and computer science. We propose the automated detection of deception based on facial micro expressions which occur spontaneously in response to the ...
Amira Himyari, Israa Hadi
doaj   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source

Clustering Time-Series Gene Expression Data with Unequal Time Intervals

, 2008
Clustering gene expression data given in terms of time-series is a challenging problem that imposes its own particular constraints, namely exchanging two or more time points is not possible as it would deliver quite different results, and also it would lead to erroneous biological conclusions.
Rueda, Luis, Bari, Ataul, Ngom, Alioune
openaire   +4 more sources

Intron‐oriented HTLV‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 mRNA

FEBS Letters, EarlyView.
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi, Yuka Hirosawa, Yusaku Sagisaka, Minami Hama, Satoshi Takeda, Jun A. Komano   +5 more
wiley   +1 more source

Deriving explanations from partial temporal information [PDF]

, 2008
The representation and manipulation of natural human understanding of temporal phenomena is a fundamental field of study in Computer Science, which aims both to emulate human thinking, and to use the methods of human intelligence to underpin engineering ...
Knight, Brian, Ma, Jixin, Petridis, Miltos   +2 more
core   +1 more source