Results 121 to 130 of about 2,116,656 (327)

Cytoplasmic delivery of antibodies through grafting a functional single complementarity‐determining region loop

open access: yesFEBS Letters, EarlyView.
We achieved cytoplasmic delivery of non‐cell‐penetrating IgGs by grafting a single functional complementarity‐determining region 1 (CDR1) from the light chain variable region (VL) of the cell‐internalizable 3D8 antibody. The engineered IgG acquired cell‐penetrating ability while maintaining antigen affinity, highlighting CDR1 grafting as a promising ...
Yerin Jeon   +5 more
wiley   +1 more source

3D FACIAL LANDMARK-BASED DECEPTION DETECTION IN VIDEO USING GRU MODEL

open access: yesMağallaẗ Al-kūfaẗ Al-handasiyyaẗ
Deception detection is an interdisciplinary field that has researchers from psychology, criminology, and computer science. We propose the automated detection of deception based on facial micro expressions which occur spontaneously in response to the ...
Amira Himyari, Israa Hadi
doaj   +1 more source

Gene expression based cancer classification

open access: yesEgyptian Informatics Journal, 2017
Cancer classification based on molecular level investigation has gained the interest of researches as it provides a systematic, accurate and objective diagnosis for different cancer types.
Sara Tarek   +2 more
doaj   +1 more source

Expressing Linear Orders Requires Exponential-Size DNNFs [PDF]

open access: yesarXiv, 2018
We show that any DNNF circuit that expresses the set of linear orders over a set of $n$ candidates must be of size $2^{\Omega(n)}$. Moreover, we show that there exist DNNF circuits of size $2^{O(n)}$ expressing linear orders over $n$ candidates.
arxiv  

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

open access: yesFEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang   +2 more
wiley   +1 more source

The Question of Expressiveness in the Generation of Referring Expressions [PDF]

open access: yesarXiv, 2010
We study the problem of generating referring expressions modulo different notions of expressive power. We define the notion of $\+L$-referring expression, for a formal language $\+L$ equipped with a semantics in terms of relational models. We show that the approach is independent of the particular algorithm used to generate the referring expression by ...
arxiv  

An integrated system for weblog study [PDF]

open access: yes, 2004
Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2004.Includes bibliographical references (p. 17).Weblogs, personal online journals, are a new medium for expression and communication.
Oshiro, Makanaokalani, 1981-
core  

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

Forkable Regular Expressions [PDF]

open access: yesarXiv, 2015
We consider forkable regular expressions, which enrich regular expressions with a fork operator, to establish a formal basis for static and dynamic analysis of the communication behavior of concurrent programs. We define a novel compositional semantics for forkable expressions, establish their fundamental properties, and define derivatives for them as ...
arxiv  

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink   +6 more
wiley   +1 more source

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