Results 131 to 140 of about 12,776,966 (376)

Deciphering Gene Expression Patterns

Developmental Cell, 2011
Large-scale studies in various model systems including Drosophila, fish, and the mouse have documented the exquisite temporal and spatial expression patterns of thousands of genes during development—making sense of it all is a major challenge in the field.
openaire   +1 more source

Evolutionary biclustering based on expression patterns

2011 11th International Conference on Intelligent Systems Design and Applications, 2011
The majority of the biclustering approaches for microarray data analysis use the Mean Squared Residue (MSR) as the main evaluation measure for guiding the heuristic. MSR has been proven to be inefficient to recognize several kind of interesting patterns for biclusters.
Pontes Balanza, Beatriz, Giráldez, Raúl, Aguilar Ruiz, Jesús Salvador   +2 more
openaire   +3 more sources

GSEA-InContext: identifying novel and common patterns in expression experiments

bioRxiv, 2018
Motivation Gene Set Enrichment Analysis (GSEA) is routinely used to analyze and interpret coordinate changes in transcriptomics experiments. For an experiment where less than seven samples per condition are compared, GSEA employs a competitive null ...
Rani K. Powers, A. Goodspeed, Harrison Pielke-Lombardo, A. Tan, J. Costello   +4 more
semanticscholar   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

A Comprehensive Functional Analysis of OsPEAMT1 and OsPEAMT2 Genes in Rice (Oryza sativa L. ssp. japonica)

Plants
Phosphoethanolamine N-methyltransferase (PEAMT) is a key enzyme that catalyzes three successive methylation steps of phosphoethanolamine (P-EA) to phosphocholine (P-Cho).
Jinde Yu, Yuying Zhang, Shaojie Ma, Xia Wen, Ning Zhao, Xiaofei Feng, Dan Zong, Jing Li   +7 more
doaj   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Genome-Wide Analysis of the CDPK Gene Family in Populus tomentosa and Their Expressions in Response to Arsenic Stress and Arbuscular Mycorrhizal Fungi Colonization

Agronomy
Calcium-dependent protein kinases (CDPKs) are crucial regulators in calcium-mediated signal transduction pathways, playing a pivotal role in plant response to abiotic stresses.
Minggui Gong, Jiajie Su, Shuaihui Wang, Youjia Wang, Weipeng Wang, Xuedong Chen, Qiaoming Zhang   +6 more
doaj   +1 more source

Analysis of the expression patterns, subcellular localisations and interaction partners of Drosophila proteins using a pigP protein trap library

Development, 2014
Although we now have a wealth of information on the transcription patterns of all the genes in the Drosophila genome, much less is known about the properties of the encoded proteins.
Nick Lowe, Johanna S. Rees, J. Roote, Ed Ryder, Irina M. Armean, G. Johnson, Emma Drummond, Helen Spriggs, Jenny Drummond, Jose P. Magbanua, Huw W. Naylor, Bénédicte Sanson, R. Bastock, Sven Huelsmann, Vitor Trovisco, Matthias Landgraf, Seymour Knowles-Barley, J. D. Armstrong, Helen White-Cooper, Celia Hansen, Roger G. Phillips, Kathryn S. Lilley, Steven Russell, D. St Johnston   +23 more
semanticscholar   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

Knockdown of the atypical protein kinase genes GhABC1K2-A05 and GhABC1K12-A07 make cotton more sensitive to salt and PEG stress

Journal of Integrative Agriculture
Activity of bc1 complex kinase (ABC1K) is an atypical protein kinase (aPK) that plays a crucial role in plant mitochondrial and plastid stress responses, but little is known about the responses of ABC1Ks to stress in cotton (Gossypium spp.).
Caixiang Wang, Meili Li, Dingguo Zhang, Xueli Zhang, Juanjuan Liu, Junji Su   +5 more
doaj   +1 more source