Results 171 to 180 of about 12,776,966 (376)

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Correlation Between Relative Gene Expression Patterns of Two Flowering locus T (MeFT1 and MeFT2) in Cassava Leaf and Flowering Traits Under Different Flowering Induction Conditions [PDF]

, 2022
Salilthip Leelawijit, Pasajee Kongsil, Piya Kittipadak, Piyada Juntawong   +3 more
openalex   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

The pattern of cytokine mRNA expression in ovarian endometriomata [PDF]

, 1997
O.A. Odukoya
openalex   +1 more source

Broad patterns of gene expression revealed by clustering analysis of tumor and normal colon tissues probed by oligonucleotide arrays.

Proceedings of the National Academy of Sciences of the United States of America, 1999
U. Alon, N. Barkai, D. Notterman, K. Gish, S. Ybarra, D. Mach, A. Levine   +6 more
semanticscholar   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Genome-Wide Analysis of the Xyloglucan Endotransglucosylase/Hydrolase (XTH) Gene Family: Expression Pattern during Magnesium Stress Treatment in the Mulberry Plant (Morus alba L.) Leaves

Plants
Mulberry (Morus alba L.), a significant fruit tree crop, requires magnesium (Mg) for its optimal growth and productivity. Nonetheless, our understanding of the molecular basis underlying magnesium stress tolerance in mulberry plants remains unexplored ...
Blessing Danso, Michael Ackah, Xin Jin, Derek M. Ayittey, Frank Kwarteng Amoako, Weiguo Zhao   +5 more
doaj   +1 more source

The Patterns of P53, E-Cadherin, β-Catenin, CXCR4 and Podoplanin Expression in Oral Squamous Cell Carcinoma Suggests a Hybrid Invasion Model: an Immunohistochemical Study on Tissue Microarrays [PDF]

Daniele Heguedusch, Giovanna Lopes Carvalho, Saygo Tomo, Emília Maria Gomes Aguiar, Marcos Custódio, Juliana Mota Siqueira, Ana Maria da Cunha Mercante, Patrı́cia Maluf Cury, Eloiza Helena Tajara, Rafael De Cicco, Vivian Petersen Wagner   +10 more
openalex   +1 more source

Referee report. For: HPAStainR: a Bioconductor and Shiny app to query protein expression patterns in the Human Protein Atlas [version 1; peer review: 1 approved]

, 2020
Mazdak Salavati
openalex   +1 more source