Developmental expression patterns of the FXR-IGF axis during early skeletal muscle growth in ducks. [PDF]
Chen L +10 more
europepmc +1 more source
Inferring Lifestyle from Gene Expression Patterns [PDF]
openaire +2 more sources
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Identification of Ubiquitin Genes and Their Expression Patterns in <i>Pinus massoniana</i> Under Infection Stress from the Pinewood Nematode. [PDF]
Chen Q +7 more
europepmc +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Transformer-based classification and interpretability of NR3C1 expression patterns in OSCC: Metabolic adaptation insights. [PDF]
Yuwanati M, Yadalam PK, Mullainathan S.
europepmc +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
UBE2S and HIF1α expression patterns and stratified analysis reveal prognostic value in esophageal squamous cell carcinoma. [PDF]
Ma M, Li M, Lv Y, Zhang Y, Pang X, Ma Y.
europepmc +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Background-Free Nanopore Decoding of microRNA Expression Patterns Using Circular Diagnostic DNA. [PDF]
Emura S +4 more
europepmc +1 more source

