Results 191 to 200 of about 7,154,169 (309)

The murine Ten-m/Odz genes show distinct but overlapping expression patterns during development and in adult brain.

, 2003
Rauch, Uwe,, Ninomiya, Yoshifumi, Fässler, Reinhard, Fässler, Reinhard,, Feng, Kang, Brandau, Oliver, Lund University., Oohashi, Toshitaka, Zhou, Xiao Hong, Rauch, Uwe, Feng, Kang,   +10 more
core   +1 more source

AMPK Pathway Activation Markers in GBM: Expression Patterns and Clinical Associations in a Real-World Study. [PDF]

Int J Mol Sci
Ferrarini F, Del Bianco P, Corrà M, Talienti T, Mauceri M, Boso D, Romanazzi G, Bedeschi M, Caccese M, Padovan M, Guerriero A, Esposito G, Desideri I, Franceschi E, Gaviani P, Buglione di Monale E Bastia M, De Salvo GL, Fiorentino A, Tesei A, Mazza T, Lombardi G, Indraccolo S.   +21 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Spatio-Temporal Expression Patterns of Connexins 43 and 30 in Hippocampal Astrocytes During Postnatal Development. [PDF]

Int J Mol Sci
Uribe-Arias A, Ribot J, Ezan P, Mailly P, Rouach N.   +4 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Clinical Evaluation of HHLA2 in Hormone Receptor-Positive Breast Cancer: Expression Patterns and Prognostic Implications. [PDF]

Biomedicines
Kwon MJ, Yi JM, Kim TH, Park HY.
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Convergence and divergence of DNA methylation and gene expression patterns in neopolyploid Arabidopsis kamchatica. [PDF]

Nat Commun
Milosavljevic S, Copetti D, Yip Tong K, Morishima A, Sese J, Robinson MD, Shimizu KK, Shimizu-Inatsugi R.   +7 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Distinct miRNA expression patterns in circulating eosinophil subtypes and their subtype-derived exosomes in allergic asthma. [PDF]

Inflamm Res
Vasyle E, Januskevicius A, Rimkunas A, Palacionyte J, Miliauskas S, Malakauskas K.   +5 more
europepmc   +1 more source