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Genome wide analysis of
BMC Genomics, 2005 Background Core promoters are the gene regulatory regions most proximal to the transcription start site (TSS), central to the formation of pre-initiation complexes and for combinatorial gene regulation.
Molina Carlos, Grotewold Erich
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Advances in genome-wide DNA methylation analysis [PDF]
BioTechniques, 2010 The covalent DNA modification of cytosine at position 5 (5-methylcytosine; 5mC) has emerged as an important epigenetic mark most commonly present in the context of CpG dinucleotides in mammalian cells.
Romi Gupta +2 more
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The value of genome-wide analysis in craniosynostosis
Frontiers in GeneticsBackground: This study assessed the diagnostic yield of high-throughput sequencing methods in a cohort of craniosynostosis (CS) patients not presenting causal variants identified through previous targeted analysis.Methods: Whole-genome or whole-exome ...
Alexandra Topa +12 more
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Genome-wide analysis of miRNAs in Carya cathayensis [PDF]
BMC Plant Biology, 2017 Background MicroRNA (miRNA) plays an important role in plant development regulation. Hickory is an economically important plant in which the amount of flowering determines its production. Results Here, 51 conserved miRNAs, which belong to 16 families and
Zhi-chao Sun +2 more
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Genome-wide analysis of insomnia disorder [PDF]
Molecular Psychiatry, 2018 Insomnia is a worldwide problem with substantial deleterious health effects. Twin studies have shown a heritable basis for various sleep-related traits, including insomnia, but robust genetic risk variants have just recently begun to be identified. We conducted genome-wide association studies (GWAS) of soldiers in the Army Study To Assess Risk and ...
Murray B. Stein +13 more
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Robust Gene-Gene Interaction Analysis in Genome Wide Association Studies. [PDF]
PLoS ONE, 2015 Genome-wide association studies (GWAS) have successfully discovered hundreds of associations between genetic variants and complex traits. Most GWAS have focused on the identification of single variants.
Yongkang Kim, Taesung Park
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Genome wide association analysis of cuticle deposition in laying hens
Poultry Science, 2023 : The cuticle is an invisible barrier that protects the internal egg contents from microorganisms entering through gas exchange pores. Eggs which have a good cuticle are least likely to be penetrated by microorganisms and improved cuticle cover should ...
Zhang Wang +8 more
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A genome‐wide analysis of the USDA Soybean Isoline Collection
The Plant Genome, 2023 The USDA Soybean Isoline Collection has been an invaluable resource for the soybean genetics and breeding community. This collection, established in 1972, consists of 611 near‐isogenic lines (NILs) carrying one or multiple genes conferring traits that ...
Erin Gilbert +4 more
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Genome-wide gene and pathway analysis [PDF]
European Journal of Human Genetics, 2010 Current GWAS have primarily focused on testing association of single SNPs. To only test for association of single SNPs has limited utility and is insufficient to dissect the complex genetic structure of many common diseases. To meet conceptual and technical challenges raised by GWAS, we suggest gene and pathway-based GWAS as complementary to the ...
Li, Luo +5 more
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