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Genome-Wide Variation in Potyviruses [PDF]
Frontiers in Plant Science, 2019 Potyviruses (family Potyviridae, genus Potyvirus) are the result of an initial radiation event that occurred 6,600 years ago. The genus currently consists of 167 species that infect monocots or dicots, including domesticated and wild plants.
Deepti Nigam +3 more
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Journal of Investigative Dermatology, 2013 WhaT is epiGeneTics? The term “epigenetics” was coined by Conrad Waddington to describe “the branch of biology which studies the causal interactions between genes and their products, which bring the phenotype into being” (Goldberg et al., 2007). Very broadly, the word has come to refer to the study of the regulation of genes, their expression, and how ...
Capell, Brian C., Berger, Shelley L.
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The future is genome-wide [PDF]
Genome Biology, 2006 A report of the annual meeting of the European Society of Human Genetics, Amsterdam, 6-9 May 2006.
Deutsch, S., Reymond, A.
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Genome Wide Methylome Alterations in Lung Cancer. [PDF]
PLoS ONE, 2015 Aberrant cytosine 5-methylation underlies many deregulated elements of cancer. Among paired non-small cell lung cancers (NSCLC), we sought to profile DNA 5-methyl-cytosine features which may underlie genome-wide deregulation.
Nandita Mullapudi +12 more
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Myopia genetics in genome-wide association and post-genome-wide association study era [PDF]
International Journal of Ophthalmology, 2019 Genome-wide association studies (GWAS) of myopia and refractive error have generated exciting results and identified novel risk-associated loci. However, the interpretation of the findings of GWAS of complex diseases is not straightforward and has ...
Xuan Liao, Qing-Qing Tan, Chang-Jun Lan
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Genome-wide approaches to schizophrenia [PDF]
Brain Research Bulletin, 2010 Schizophrenia (SZ) is a common and severe psychiatric disorder with both environmental and genetic risk factors, and a high heritability. After over 20 years of molecular genetics research, new molecular strategies, primarily genome-wide association studies (GWAS), have generated major tangible progress.
Jubao, Duan +2 more
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Genome wide study of tardive dyskinesia in schizophrenia
Translational Psychiatry, 2021 Tardive dyskinesia (TD) is a severe condition characterized by repetitive involuntary movement of orofacial regions and extremities. Patients treated with antipsychotics typically present with TD symptomatology.
Keane Lim +13 more
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Improved heritability estimation from genome-wide SNPs [PDF]
, 2012 Narrow-sense heritability (h(2)) is an important genetic parameter that quantifies the proportion of phenotypic variance in a trait attributable to the additive genetic variation generated by all causal variants.
Johnson, Michael R. +7 more
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Genome-Wide Variation in Betacoronaviruses
Journal of Virology, 2021 Natural infection with SARS-CoV-2 and vaccines triggers the formation of antibodies against the S glycoprotein, which are detected by antibody-based diagnostic tests. Our analysis showed that variation in the S glycoprotein is a general feature of all species in the genus Betacoronavirus , including three species ...
Katherine LaTourrette +4 more
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Genome-wide association study of receptive language ability of 12 year olds [PDF]
, 2013 Purpose: We have previously shown that individual differences in measures of receptive language ability at age 12 are highly heritable. The current study attempted to identify some of the genes responsible for the heritability of receptive language ...
Hanscombe, K.B. +32 more
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