Results 31 to 40 of about 3,210,341 (315)
Genome-wide analysis of insomnia disorder [PDF]
Molecular Psychiatry, 2018 Insomnia is a worldwide problem with substantial deleterious health effects. Twin studies have shown a heritable basis for various sleep-related traits, including insomnia, but robust genetic risk variants have just recently begun to be identified. We conducted genome-wide association studies (GWAS) of soldiers in the Army Study To Assess Risk and ...Murray B. Stein, Michael J. McCarthy, Chia-Yen Chen, Sonia Jain, Joel Gelernter, Feng He, Steven G. Heeringa, Ronald C. Kessler, Matthew K. Nock, Stephan Ripke, Xiaoying Sun, Gary H. Wynn, Jordan W. Smoller, Robert J. Ursano +13 moreopenaire +6 more sourcesGenetic risk factors for ischaemic stroke and its subtypes (the METASTROKE Collaboration): a meta-analysis of genome-wide association studies [PDF]
, 2012 <p>Background - Various genome-wide association studies (GWAS) have been done in ischaemic stroke, identifying a few loci associated with the disease, but sample sizes have been 3500 cases or less.Furie, K., Benn, M. (Marianne), Carty, C., Reiner, AP, Palmer, Colin N.A., Markus, Hugh S, Lindgren, Arne,, Fornage, Myriam, Algra, Ale, Nalls, Mike A, de Bakker, P.I.W., Rothwell, Peter M., Worrall, Bradford B, Nalls, Mike A., Kuhlenbaeumer, Gregor, Deary, Ian, Levi, C., Palmer, Colin N. A., Delavaran, Hossein,, Berger, K., Reiner, A.P., Sharma, P, The Australian Stroke Genetics Collaborative, including Jonathan Golledge, Higgins, P., Palmer, CN, Worrall, BB, Vicente, A.M. (Astrid M), Helgadottir, A, Thorleifsson, G. (Gudmar), Rothwell, Peter M, Kuhlenbäumer, G., Pandolfo, M, Khan, M.I. (Muhammad), Khan, M.S., Stefansson, K, Wiggins, Kerri L., Lindgren, Arne, Vicente, Astrid M., Hofman, A., Bis, JC, Kittner, Steven J., Kittner, Steven, Boncoraglio, G. (Giorgio Battista), Schmidt, Reinhold, Palmer, C.N.A. (Colin), Nordestgaard, Børge G., Paré, Guillaume, Wiggins, K.L. (Kerri), Delavaran, H, de Bakker, Paul I. W., Cheng, Y.-C. (Yu-Ching), Sale, P. (Patrizio), Cheng, YC, Wiggins, K.L., Meschia, JF, Pandolfo, M. (Massimo), Levi, C, Sudlow, C. (Cathie), Saleheen, D, ?, ?, Ringelstein, E.B., Fomage, Myriam, Bevan, S, Wiggins, KL, Gretarsdottir, S. (Solveig), Zwart, J-A. (John-Anker), Nordestgaard, B.G., Deary, I.J. (Ian), Kuhlenbäumer, G, Mosley, Thomas H, Paré, G., Nalls, M.A., Algra, A. (Ale), Hopewell, Jemma C., Oliveira, SA, Berger, K. (Klaus), Traylor, M, Seshadri, S., Boncoraglio, G.B., Valdimarsson, Einar, Wiggins, Kerri L, van Zuydam, Natalie R., Lemmens, Robin, Carty, Cara, Worrall, B.B. (Bradford B.), Fernandez-Cadenas, I. (Israel), Benn, M, Achterberg, Sefanja, Vicente, Astrid M, Thijs, V, Ikram, M Arfan, Doney, AS, Dichgans, M, Zuydam, N.R. van, Wellcome Trust Case Control Consortium 2 (WTCCC2), Norrving, Bo,, Bakker, P.I.W. (Paul) de, Furie, K.L. (Karen), Nalls, M.A. (Michael), Yadav, S, Fernandez-Cadenas, I., Longstreth, W.T., Paré, G. (Guillaume), Mitchell, BD, Bakker, P.I.W. de, Norrving, B., Holliday, Elizabeth G., van Zuydam, N.R., Achterberg, S, van Zuydam, N.R,, Traylor, Mathew, Reiner, Alex P, Sharma, Pankaj, Montaner, J., Rothwell, PM, Kee, Weang, O'Donnell, M., Carty, C. (Cara), Cheng, Yu-Ching, Carty, C, Lund University., Rothwell, P.M. (Peter), Pandolfo, Massimo, Schmidt, Helena, Int Stroke Genetics Consortium, Norrving, Bo, de Bakker, Paul I W, Davies, Gail, Chen, W-M., Gretarsdottir, S., Gschwendtner, A., Bevan, Steve, Cheng, Y.-C., Abboud, S, Sharma, P. (Pankaj), Doney, Alexander S.F.; id_orcid, Norrving, B. (Bo), Benn, M., Ferro, Jose M., Slowik, A, Walters, Matthew, Yadav, S. (Sunaina), Delavaran, H. (Hossein), Holliday, E.G., Lindgren, A. (Arne), Meschia, James F, Farrall, M. (Martin), Pera, J, Longstreth, W. T., Oliveira, Sofia A., Helgadottir, H.T. (Hafdis), Ferro, Jose M, Reiner, Alex P., Slowik, A., Ringelstein, E.Bernd, Thorsteinsdottir, U, International Stroke Genetics Consortium, Sudlow, C., Longstreth, W, Chen, W.M., Malik, R. (Rainer), Mosley, Thomas H., Markus, H.S., Thorsteinsdottir, U. (Unnur), Abboud, S., Psaty, B.M. (Bruce), Mosley, T.H., Thijs, Vincent, Ikram, Arfan, Saleheen, D., Walters, M.R. (Matthew), Traylor, M., de Bakker, P.I., Montaner, J, O'Donnell, M, Oliveira, Sofia A, Ho, W.K., Kostulas, Konstantinos, Hofman, Albert, Palmer, CNA, Levi, C. (Christopher), Chen, W.-M., Higgins, P, Bevan, S., Longstreth Jr, W.T., Doney, A.S., Mitchell, B.D. (Braxton), Seshadri, S. (Sudha), Sale, M, Ho, WK, Furie, Karen, Delavaran, H., Sale, M., Valdimarsson, E, Cheng, Y.C., Slowik, A. (Agnieszka), DeStefano, A.L. (Anita), Rosand, J. (Jonathan), Davies, G. (Gail), Helgadottir, Anna, Psaty, Bruce M., O'Donnell, M. (Martin), Australian Stroke Genetics Collaborative, Wellcome Trust Case Co, Mitchell, Braxton D., Walters, M., Doney, ASF, van Zuydam, Natalie R, de Bakker, PIW, Rosand, Jonathan, Holliday, Elizabeth G, Fernandez-Cadenas, I, Bis, Joshua C, Delavaran, Hossein, Bevan, S. (Steve), Achterberg, S. (Sefanja), Valdimarsson, E. (Einar), Lemmens, R, Bis, J.C. (Joshua), Benn, Marianne, Parati, E.A., Kubisch, C. (Christian), Gschwendtner, A. (Andreas), Hofman, Bert, Farrall, M, Montaner, J. (Joan), Meschia, J.F. (James F.), Khan, Muhammad Saleem, Kittner, Steven J, Levi, Christopher, Sudlow, Catherine; id_orcid, Davies, G, Palmer, C.N.A., Oliveira, S.A. (Sofia), Psaty, Bruce M, Rothwell, P.M., Pera, M.F. (Martin ), Parati, E.A. (Eugenio), Oliveira, S.A., Furie, K, Dichgans, M., van Zuydam, NR, Boncoraglio, Giorgio B, Kittner, S, Berger, Klaus, Pera, Joanna, Davies, G., Higgins, P. (Peter), Pandolfo, M., Holliday, EG, Valdimarsson, E., Rosand, J., Palmer, Colin N A, Ho, Weang Kee, Deary, I., Bis, J.C., Lemmens, R., Clarke, Robert, Boncoraglio, Giorgio B., Sudlow, C, Kuhlenbäumer, G. (Gregor), Schmidt, H., Abboud, Sherine, Ferro, M.T. (María), Australian Stroke Genetics Collabo, Higgins, Peter, Worrall, Bradford B., Mitchell, Braxton D, Malik, R., Boncoraglio, GB, Lindgren, A, Clarke, R., Thorsteinsdottir, Unnur, Fornage, M., Mosley, TH, Ringelstein, E Bernd, Parati, Eugenio A, DeStefano, A.L., Lemmens, R. (Robin), Stefansson, K., Markus, HS, Chen, Wei-Min, Doney, Alexander S. F., Ringelstein, EB, Bis, Joshua C., Ikram, M.A., Rosand, J, Ferro, J. M., Norrving, B, Farrall, M., Seshadri, S, International Stroke Genetics Consortium., Walters, Mathew, Kostulas, K. (Konstantinos), Thorleifsson, G, Doney, Alexander S.F., Malik, R, Destefano, AL, Slowik, Agnieszka, Thijs, V. (Vincent), Lindgren, A., Longstreth, Wt, Nordestgaard, B.G. (Børge), Clarke, R. (Robert), Stefansson, Kan, Kostulas, K., Destefano, Anita L, Schmidt, R, Fomage, M., Farrall, Martin, Ferro, J.M., Schmidt, R. (Reinhold), Schmidt, H, WTCCC 2, Palmer, Colin N.A.; id_orcid, Helgadottir, A., Fernandez-Cadenas, Israel, Stefansson, Kari, Nordestgaard, BG, Ikram, M. Arfan, Sharma, P., Abboud, S. (Shimon), Clarke, R, Parati, EA, Gretarsdottir, Solveig, Berger, K, Hofman, A. (Albert), Palmer, C.N., Kittner, S., Algra, A, Fornage, M. (Myriam), Ringelstein, E.B. (E. Bernd), Nalls, MA, Fornage, M, O'Donnell, Martin, Longstreth, W., Kittner, T. (Thomas), Algra, A., Thorsteinsdottir, U., Kittner, S.J., Sale, Michele, Fomage, M, Reiner, A. (Alexander), Kittner, SJ, Ikram, MA, Deary, I, Worrall, B.B., Ferro, JM, Gschwendtner, Andreas, Dichgans, Martin, Holliday, E.G. (Elizabeth), Thorleifsson, G., Gschwendtner, A, Schmidt, R., de Bakker, Paul I.W., Nordestgaard, Børge G, Traylor, M. (Matthew), Mosley, T.H. (Thomas), DeStefano, Anita L., Doney, A.S.F. (Alex), Nordestgaard, Borge G., Thorleifsson, Gudmar, Yadav, S., Kostulas, K, Vicente, A.M., Australian Stroke Genetics Collaborative, Wellcome Trust Case Control Consortium 2 (WTCCC2), Psaty, BM, de Bakker, PI, Parati, Eugenio A., Saleheen, Danish, Khan, MS, Vicente, AM, Walters, M, Psaty, B.M., Hofman, A, Hopewell, Jemma C, Meschia, J.F., Pera, J., Doney, A.S.F., Mitchell, B.D., Markus, Hugh S., Kuhlenbäumer, Gregor, Hopewell, JC, Zuydam, N.R. (Natalie) van, Chen, WM, Thijs, V., Gretarsdottir, S, Yadav, Sunaina, Markus, H.S. (Hugh), Hopewell, J., Ringelstein, E. Bernd, Sudlow, Cathie, Paré, G, Montaner, Joan, Ho, W.K. (Weang Kee), Achterberg, S., Doney, Alexander S F, Seshadri, Sudha, Hopewell, J.C., Meschia, James F., Ikram, M.A. (Arfan), Malik, Rainer, Hopewell, Jemma, Traylor, Matthew +402 morecore +1 more sourceINFERRING GENOME-WIDE MOSAIC STRUCTURE [PDF]
Biocomputing 2009, 2008 Genetic recombination plays two essential biological roles. It ensures the fidelity of the transmission of genetic information from one generation to the next and it generates new combinations of genetic variants. Therefore, recombination is a critical process in shaping arrangement of polymorphisms within populations.Qi Zhang 0025, Wei Wang 0010, Leonard McMillan, Fernando Pardo-Manuel de Villena, David Threadgill +4 moreopenaire +3 more sourcesSimultaneous Analysis of All SNPs in Genome-Wide and Re-Sequencing Association Studies [PDF]
, 2008 Testing one SNP at a time does not fully realise the potential of genome-wide association studies to identify multiple causal variants, which is a plausible scenario for many complex diseases.Maria De Iorio, John C Whittaker, Balding, DJ, De Iorio Maria, Clive J. Hoggart, Hoggart, Clive J, Balding, David J, David J Balding, Clive J Hoggart, Whittaker, John C, Balding David J., De Iorio, Maria, John C. Whittaker, Whittaker John C., De Iorio, M, Whittaker, JC, Hoggart Clive J., Hoggart, CJ, David J. Balding +18 morecore +1 more sourceGenome-wide Association Studies
, 2013 Genome-wide association studies (GWAS) are a powerful hypothesis-free tool for the dissection of susceptibility to common heritable human diseases, including osteoporosis. To date, more than 2000 loci for common human diseases have been identified by GWAS.Duncan, Emma, Brown, Matthewopenaire +5 more sourcesGenome-Wide Association Studies in Atherosclerosis [PDF]
Current Atherosclerosis Reports, 2011 Cardiovascular disease remains the major cause of worldwide morbidity and mortality. Its pathophysiology is complex and multifactorial. Because the phenotype of cardiovascular disease often shows a marked heritable pattern, it is likely that genetic factors play an important role.Sivapalaratnam, S., Motazacker, M.M., Maiwald, S., Hovingh, G.K., Kastelein, J.J.P., Levi, M., Trip, M.D., Dallinga-Thie, G.M. +7 moreopenaire +4 more sourcesTargeting 160 candidate genes for blood pressure regulation with a genome-wide genotyping array [PDF]
, 2009 The outcome of Genome-Wide Association Studies (GWAS) has challenged the field of blood pressure (BP) genetics as previous candidate genes have not been among the top loci in these scans.Döring, Angela, Illig, T, Peeter Juhanson, Katrin Kepp, Juhanson, P., Juhanson, P, Samani, Nilesh, Philip Howard, Caulfield, Mark J., P. B. Munroe (7602386), Veldre, G, Farrall, Martin, Lichtner Peter, Dobson, RJ, Viigimaa, M., C. Gieger (7609259), Morris Brown, Putku Margus, Wichmann, H.-E., Illig, T., Siim Sõber, Gudrun Veldre, Shaw-Hawkins, Sue, Kelgo, Piret, Illig Thomas, R. J. Dobson (7602557), Samani, N, Samani Nilesh, Laan, Maris, HYPertens ESTonia Study, A. Dominiczak (7611551), Munroe, Patricia B., Kepp, K, John Connell, T. Illig (7609322), Samani, N., M. Putku (7602647), Viigimaa Margus, Farrall Martin, Brown, M, Peter Lichtner, Sober, S, A. Döring (7609562), Lichtner, Peter, P. Howard (7611350), Piret Kelgo, Juhanson Peeter, Dobson, Richard J.; id_orcid, Org, E, Farrall, M, Dobson, R.J., Meitinger, T, Veldre, Gudrun, E. Org (7602644), Kooperative Gesundheitsforschung in der Region Augsburg Study, Lichtner, P., H-Erich Wichmann, Martin Farrall, Kepp, Katrin, Gieger, Christian, HYPertension in ESTonia Study, Margus Putku, Newhouse, SJ, Onipinla Abiodun, Caulfield Mark J., Meitinger, T., M. Laan (7602659), Caulfield, MJ, Maris Laan, Eyheramendy, S., Onipinla, A., Newhouse, S.J., M. Viigimaa (7602620), Gieger, C, Dominiczak, A., Kelgo, P, Onipinla, A, Döring Angela, Newhouse, Stephen J.; id_orcid, Shaw-Hawkins Sue, Susana Eyheramendy, Munroe, PB, Klopp, Norman, Newhouse, Stephen J., Brown, Morris, Putku, Margus, M. Farrall (6522599), Wichmann, H.-Erich, Meitinger Thomas, S. Eyheramendy (7611197), Wichmann, Heinz-Erich, Putku, M, M. Brown (3020991), Gieger, C., Christian Gieger, Döring, A., Dobson, Richard J., Munroe, P.B., Juhanson, Peeter, Lichtner, P, Richard J Dobson, Org, E., H-E. Wichmann (7611602), Doering, Angela, Howard Philip, Kepp, K., Org, Elin, Kelgo Piret, Anna Dominiczak, Klopp, N., S. Shaw-Hawkins (7602380), Org Elin, Gieger Christian, Dominiczak Anna, Margus Viigimaa, Viigimaa, Margus, Newhouse Stephen J., K. Kepp (7611593), Sue Shaw-Hawkins, Stephen J Newhouse, Howard, P., Munroe Patricia B., Wichmann, H. Erich, P. Kelgo (7611596), Wichmann H.-Erich, Eyheramendy, S, Kooperative Gesundheitsforsch, Putku, M., M. J. Caulfield (7602383), Patricia B Munroe, Howard, P, Angela Döring, Eyheramendy, Susana, Nilesh Samani, Veldre Gudrun, Kepp Katrin, Sõber Siim, J. . Connell (7611608), Wichmann, HE, MRC British Genet Hypertens Study, Laan, M., Laan Maris, Elin Org, Connell, J, Illig, Thomas, Meitinger, Thomas, Doring, A, Viigimaa, M, Thomas Illig, N. Klopp (7611599), S. J. Newhouse (7602371), Connell John, S. Sõber (7602650), Shaw-Hawkins, S, Onipinla, Abiodun, Shaw-Hawkins, S., Dobson Richard J., Dominiczak, A, Klopp Norman, T. Meitinger (14191), Abiodun Onipinla, G. Veldre (7602656), Sõber, Siim, Thomas Meitinger, Eyheramendy Susana, P. Lichtner (7611605), A. Onipinla (7602377), Mark J Caulfield, Klopp, N, Caulfield, M.J., N. Samani (7611611), P. Juhanson (7602641), Dominiczak, Anna, Veldre, G., Connell, J., Connell, John, Norman Klopp, MRC British Genetics of Hypertension Study, Brown, M., Sõber, S., Howard, Philip, Brown Morris, Laan, M +182 morecore +1 more source
