Results 41 to 50 of about 3,210,341 (315)
Common genetic variants associated with disease from genome-wide association studies are mutually exclusive in prostate cancer and rheumatoid arthritis [PDF]
, 2011 Objectives: To investigate if potential common pathways exist for the pathogenesis of autoimmune disease and prostate cancer (PrCa). To ascertain if the single nucleotide polymorphisms (SNPs) reported by genome-wide association studies (GWAS) as being ...Donovan, Jenny, Rosalind A. Eeles, Eyre, S, Kote-Jarai, Zsofia, Goh, Chee L., Neal, David E., Freddie C. Hamdy, Giles, GG, Kote-Jarai, Z, Giles, Graham, Eyre, S; id_orcid, Ali Amin Al Olama, Govindasami, K, Muir, K R; id_orcid, Al Olama, AA, Guy, M, Easton, Douglas F., Giles, G G, Govindasami, Koveela, Hamdy, Freddie C., Donovan, J L, Benlloch, Sara, Chee L. Goh, Guy, Michelle, Goh, CL, Zsofia Kote‐Jarai, Muir, KR, Al Olama, Ali Amin, Al Olama, A A, Eeles, R A, Neal, D E, Hamdy, FC, Benlloch-Garcia, S, Donovan, JL, Eyre, Steve, Muir, Kenneth, Neal, DE, Sara Benlloch‐Garcia, Severi, G, Eeles, RA, David E. Neal, Steve Eyre, Orozco, Gisela, Hamdy, F C, Michelle Guy, Hamdy, Freddie, Goh, C L, Severi, Gianluca, Koveela Govindasami, Jenny L. Donovan, Kenneth R. Muir, Graham G. Giles, Easton, DF, Gianluca Severi, Orozco, G, Douglas F. Easton, Easton, D F, Gisela Orozco, Eeles, Rosalind A. +58 morecore +1 more sourceHeritability of variation in glycaemic response to metformin:a genome-wide complex trait analysis [PDF]
, 2014 Background: Metformin is a first-line oral agent used in the treatment of type 2 diabetes, but glycaemic response to this drug is highly variable.Ahlqvist, Emma,, Deshmukh, Harshal, Pearson, Ewan R., Deshmukh, H, Colhoun, Helen M, Morris, Andrew D., Morris, Andrew D, Groop, Leif,, Colhoun, HM, McCarthy, Mark I, Zhou, K, Palmer, Colin N A, Yang, J, Palmer, Colin N.A.; id_orcid, Zuydam, NV, Groop, L, Sham, Pak C, McCarthy, Mark, Spencer, Chris C, Donnelly, Lousie, Palmer, Colin N. A., Spencer, Chris C., Zhou, KX, Yang, Jian, Spencer, CC, Lund University., Palmer, CN, Donnelly, Louise, Li, M, McCarthy, MI, Van Zuydam, Natalie, Palmer, CNA, Zhou, Kaixin, Spencer, Chris, Pearson, Ewan R.; id_orcid, McCarthy, ML, Donnelly, L, Van Zuydam, N, Li, Miaoxin, Morris, AD, Groop, Leif, Sham, PC, McCarthy, Mark I., Ahlqvist, E, Groop, Lief, Pearson, Ewan R, Pearson, ER, Colhoun, Helen M., Sham, Pak C., Ahlqvist, Emma +49 morecore +1 more sourceGenome wide association study of frost tolerance in wheat
Scientific Reports, 2022 Winter wheat growing areas in the Northern hemisphere are regularly exposed to heavy frost. Due to the negative impact on yield, the identification of genetic factors controlling frost tolerance (FroT) and development of tools for breeding is of prime ...Behnaz Soleimani, Heike Lehnert, Steve Babben, Jens Keilwagen, Michael Koch, Fernando Alberto Arana-Ceballos, Yuriy Chesnokov, Tatyana Pshenichnikova, Jörg Schondelmaier, Frank Ordon, Andreas Börner, Dragan Perovic +11 moredoaj +1 more sourceGenome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits [PDF]
, 2011 Nonalcoholic fatty liver disease (NAFLD) clusters in families, but the only known common genetic variants influencing risk are near PNPLA3. We sought to identify additional genetic variants influencing NAFLD using genome-wide association (GWA) analysis ...Palmer Cameron D., Schwartz, SM, Benjamin F Voight, Fox, Caroline S., Hwang, Shih-Jen, GIANT Consortium, Launer, Lenore, Hernaez, R, Melissa E. Garcia, Hwang, SJ, Pietiläinen, Kirsi Hannele, Harris, Tamara B, Mitchell, Braxton D., CRISPONI, LAURA, Butler, Johannah L, Massaro, J.M., Gudnason, V., Feitosa, MF, Jeanne M. Clark, Massaro, J., Jørgensen, Torben, O'Donnell Christopher J., Stephen M. Schwartz, Schwartz SM, Palmer, C., Eiriksdottir, Gudny, Joel N Hirschhorn, Kao W. H. Linda, Laura M. Yerges-Armstrong, Stephen M Schwartz, Jeanne M Clark, Borecki Ingrid B., Mitchell, Braxton, Smith, AV, null null, Palmer, C.D., Kao, W.H.L., Johannah L. Butler, Butler, Johannah L., Borecki, IB, Palmer CD, Salomaa, V., Hirschhorn, Joel, Borecki, Ingrid B., Johannah L Butler, Speliotes, Elizabeth K, Fox Caroline S., Shuldiner, Alan R., Fox CS, Hoffmann, Udo, Palmer, CD, Nalls, Michael, Garcia, Melissa E, Hwang SJ, Wu, Jun, Mary F Feitosa, Massaro, Joseph M., Eiriksdottir G, Schadt, EE, Voight, Benjamin F, Nalls, Michael A., Clark, Jeanne M., Eiriksdottir, G, Smith AV, O'Donnell, CJ, Sahani DV, NASH CRN, Schwartz Stephen M., Lauren J Kim, CJ, Butler Johannah L., Speliotes, Elizabeth K., Tamara B Harris, Speliotes, E.K., Feitosa, Mary F., Joseph M. Massaro, Caroline S. Fox, Smith, Albert V, Launer, Lenore J, Shuldiner Alan R., GOLD Consortium, Hoffmann, U, Harris, Tamara, Tamara B. Harris, Garcia Melissa E., Kao, W. H Linda, Albert V. Smith, Mitchell BD, Smith, A.V., Voight, BF, Voight, Benjamin F., Mary F. Feitosa, Alan R Shuldiner, Kim, L.J., Kao, W H Linda, Speliotes EK, Siscovick, DS, Schadt, Eric E., Fox, C.S., Vilmundur Gudnason, Sahani, Dushyant V, Ruben Hernaez, Raychaudhuri, Soumya, Cameron D Palmer, Dushyant V Sahani, Salomaa, Veikko, O'Donnell, Christopher J., Feitosa, Mary, Shuldiner AR, Carr, J Jeffrey, Harris, T.B., Speliotes Elizabeth K., Salomaa, V, Posthuma, D., Tomas, Marta, Palmer, Cameron D, Tomas, M, Wu Jun, Siscovick David S., Launer Lenore J., Palmer, Cameron, et al., de Geus, E.J.C.; id_orcid, Butler, J.L., Clark Jeanne M., Hernaez, R., Mitchell, Braxton D, Borecki, Ingrid B, Shuldiner, A.R., Voight Benjamin F., Benjamin F. Voight, Kao, WH Linda, Lenore J. Launer, Feitosa MF, Siscovick, David, Nalls, M.A., Carr, J. Jeffrey, Clark, JM, Garcia, Melissa E., Lenore J Launer, Hirschhorn Joel N., Hwang, S.J., Eiriksdottir, G., Launer, L.J., Laura M Yerges-Armstrong, Melissa E Garcia, Hwang, S., Christopher J O'Donnell, Yerges-Armstrong, Laura M., Clark, J., Kim Lauren J., Launer, Lenore J., Hirschhorn JN, Harris, Tamara B., Michael A. Nalls, Launer LJ, Boomsma, D.I.; id_orcid, J Jeffrey Carr, Massaro, JM, Braxton D. Mitchell, Posthuma, D.; id_orcid, Heijer, M. den, Shih-Jen Hwang, Siscovick, David S., Mitchell, BD, Siscovick DS, Gudnason V, Yerges-Armstrong, L.M., Launer, LJ (Lenore), Gudnason, Vilmundur, Veikko Salomaa, de Geus, E.J.C., O' DONNELL, Willemsen, G.; id_orcid, Mitchell, B., Shuldiner, Alan, Kim, Lauren J, Sahani Dushyant V., Smith Albert V., David S Siscovick, Schadt, Eric, Kao WH, Fox, CS, David S. Siscovick, Carr JJ, Butler, Johannah, Massaro, Joseph, Hoffmann U, Garcia, Melissa, Tomas Marta, Mitchell Braxton D., Christopher J. O'Donnell, Lokki, Marja-Liisa, Gudnason Vilmundur, Fox, Caroline, DIAGRAM Consortium, Schadt, E.E., Tomas M, Hirschhorn, J.N., Jun Wu, Nalls, M., Ingrid B Borecki, Launer, L., Harris TB, Palmer, Cameron D., O'Donnell, C.J., Nalls MA, Voight BF, Borecki IB, Salomaa V, Massaro, Joseph M, Voight, B.F., Nalls, MA, O'Donnell, Christopher J, Garcia, M., Harris Tamara B., Kao, W., Kao, WH, Elizabeth K Speliotes, Gudnason, V, Siscovick, D.S., Yerges-Armstrong, Laura, Siscovick, David S, Cameron D. Palmer, Smith, Albert, Garcia ME, Marta Tomas, Clark, Jeanne M, Eric E. Schadt, Hottenga, J.J., Wu, J, Caroline S Fox, Joel N. Hirschhorn, Wu, J., Hoffmann Udo, Schadt EE, Albert V Smith, Carr J. Jeffrey, Sahani, D.V., J. Jeffrey Carr, Michael A Nalls, Feitosa, Mary F, Kao, W.H., O'Donnell, Christopher, Kim LJ, Nalls Michael A., Feitosa Mary F., Schwartz, S.M., Smith, Albert V., Shuldiner, Alan R, Voight, Benjamin, Wu J, Alan R. Shuldiner, Borecki, Ingrid, Massaro Joseph M., Lauren J. Kim, Schwartz, Stephen M, SCUTERI, ANGELO, Kao, WHL, Speliotes, Elizabeth, Kim, LJ, Clark, Jeanne, Carr, J.J., Nalls, Michael A, Feitosa, M.F., Harris, TB, Willemsen, G., Hirschhorn, Joel N., Clark JM, Yerges-Armstrong, L., Ingrid B. Borecki, Eric E Schadt, Butler, J., Butler JL, Schwartz, Stephen, Yerges-Armstrong LM, Garcia, M.E., Hernaez Ruben, Shuldiner, AR, GIANT, Boomsma, D.I., Kim, L., Elizabeth K. Speliotes, O’Donnell, C., Clark, J.M., Yerges-Armstrong, Laura M, Kim, Lauren J., Garcia, ME, Joseph M Massaro, Mitchell, B.D., Massaro JM, Speliotes, EK, Kim, Lauren, Udo Hoffmann, Jansson, John-Olov,, W H Linda Kao, MAGIC Investigators, Launer, LJ, Shuldiner, A., Hirschhorn, Joel N, Salomaa Veikko, Dushyant V. Sahani, Hwang Shih-Jen, Tomas, M., Hernaez R, Geus, E.J.C. de, Borecki, I.B., Kao, W. H. Linda, Hwang, Shih Jen, Butler, JL, Sahani, Dushyant, Hirschhorn, JN, Sahani, Dushyant V., Speliotes, E., YERGES ARMSTRONG LM, Yerges-Armstrong Laura M., Hernaez, Ruben, Eiriksdottir Gudny, Sahani, DV, Gudny Eiriksdottir, Braxton D Mitchell, Schadt Eric E., Schadt, Eric E, Hoffmann, U., PAOLISSO, Giuseppe, Schwartz, Stephen M., W. H. Linda Kao, Carr, JJ, Yerges-Armstrong, LM, Fox, Caroline S +329 morecore +1 more sourceGenome‐wide allele‐ and strand‐specific expression profiling
Molecular Systems Biology, 2009 Recent reports have shown that most of the genome is transcribed and that transcription frequently occurs concurrently on both DNA strands. In diploid genomes, the expression level of each allele conditions the degree to which sequence polymorphisms ...Julien Gagneur, Himanshu Sinha, Fabiana Perocchi, Richard Bourgon, Wolfgang Huber, Lars M Steinmetz +5 moredoaj +1 more sourceOvarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations
Pediatric Blood &Cancer, EarlyView.ABSTRACT
As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.Dominik T. Schneider, Kris‐Ann Schultz, Nora Schnitzler, Michael Abele, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Ines B. Brecht, Maja Cesen, Andrea Ferrari, Michaela Kuhlen, Malgorzata A. Krawczyk, Ricardo Lopez‐Almaraz, Yves Reguerre, Calogero Virgone, Daniel Orbach +15 morewiley +1 more source
