Results 191 to 200 of about 12,776,966 (376)

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Interpreting patterns of gene expression with self-organizing maps: methods and application to hematopoietic differentiation.

Proceedings of the National Academy of Sciences of the United States of America, 1999
P. Tamayo, D. Slonim, J. Mesirov, Q. Zhu, S. Kitareewan, E. Dmitrovsky, E. Lander, T. Golub   +7 more
semanticscholar   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Additional file 3 of Genome-wide analysis and expression patterns of lipid phospholipid phospholipase gene family in Brassica napus L.

, 2021
Wei Su, Ali Raza, Liu Zeng, Ang Gao, Yan Lv, Xiaoyu Ding, Yong Cheng, Xiling Zou   +7 more
openalex   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Elevated Expression of CHAF1A in Hepatocellular Carcinoma Progression and Immune Modulation

Clinical and Experimental Gastroenterology
Jiajing Li,1 Ting Zhang,2 Qi Liu,2 Qian Du3 1The Diagnostics Laboratory, Affiliated Hospital to Zunyi Medical University, Zunyi, Guizhou, 563000, People’s Republic of China; 2Affiliated Hospital to Zunyi Medical University, Zunyi, Guizhou, 563000, People’
Li J, Zhang T, Liu Q, Du Q
doaj  

Systematic integration of RNA-Seq statistical algorithms for accurate detection of differential gene expression patterns [PDF]

, 2014
Panagiotis Moulos, Pantelis Hatzis
openalex   +1 more source

Spatiotemporal patterns of gene expression around implanted silicon electrode arrays

, 2021
Cort H. Thompson, Akash Saxena, Nicholas Heelan, Joseph W. Salatino, Erin K. Purcell   +4 more
openalex   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

GAP-43 transgenic mice: dispersed genomic sequences confer a GAP-43- like expression pattern during development and regeneration [PDF]

, 1994
Jens Vanselow, Ed Grabczyk, Ping Jiang, Manfred Baetscher, Shu‐Chun Teng, MC Fishman   +5 more
openalex   +1 more source