Results 251 to 260 of about 7,154,169 (309)

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Comprehensive analysis of IDD family genes and their expression patterns in barley. [PDF]

BMC Plant Biol
Yin C, Li J, Liu W, Zeng J, Ma W, Feng X.   +5 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Conserved mRNA expression patterns of the Klotho family in canine mammary tumors and human breast cancer. [PDF]

Sci Rep
Kluppel L, Gee RRF, Plavec T, Švara T, Gutierrez JSS, Hoyos Sanchez MC, Erjavec V, Emmons J, Sheppard H, Tacer M, Štepihar D, Olivier AK, Gombač M, Rosa F, Tacer KF.   +14 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Developmental and Light-Induced Expression Patterns of Phototransduction Pathway Genes in Large Yellow Croaker (<i>Larimichthys crocea</i>). [PDF]

Genes (Basel)
Huang S, Xu H, Huang W, Li L, Ji Q, Wu T, Wu L, Song W.   +7 more
europepmc   +1 more source

Impact of Preweaning Vaccination on Host Gene Expression Patterns Linked to Future Bovine Respiratory Disease Development in Beef Calves. [PDF]

Vaccines (Basel)
McAllister HR, Ramirez BI, Capik SF, Harvey KM, Morley PS, Valeris-Chacin RJ, Karisch BB, Woolums AR, Thompson AC, Scott MA.   +9 more
europepmc   +1 more source

Analysis of gene expression patterns modulated by tuberculous pleural effusion-derived exosomal miRNAs in lung cancer. [PDF]

Front Genet
Park G, Kang HJ, Hong Y, Lee JJ, Shin SH, Hong JY.   +5 more
europepmc   +1 more source

Clinicopathological features and immune checkpoint expression patterns in dMMR early gastric cancer: a retrospective pilot study. [PDF]

BMC Cancer
Yokotani Y, Sakamoto N, Matsuo M, Nakahata Y, Okuyama H, Mukai R, Nagano J, Obora A, Murakami Y, Kojima T, Yagi N.   +10 more
europepmc   +1 more source

Obesity and Pro-Inflammatory Cytokines: Gene Expression Patterns Within Cervical Cancer Progression. [PDF]

In Vivo
García-Montoya IA, Picazo-Pérez L, Arellano-Ortiz AL, Salcedo-Vargas M, Silva-Espinoza JC, Jiménez-Vega F.   +5 more
europepmc   +1 more source