Results 91 to 100 of about 132,242 (193)

Unsupervised empirical Bayesian multiple testing with external covariates

, 2008
In an empirical Bayesian setting, we provide a new multiple testing method, useful when an additional covariate is available, that influences the probability of each null hypothesis being true.
Ferkingstad, Egil, Frigessi, Arnoldo, Kong, Augustine, Rue, Håvard, Thorleifsson, Gudmar   +4 more
core   +2 more sources

(Non)Parallel Evolution [PDF]

, 2018
Parallel evolution across replicate populations has provided evolutionary biologists with iconic examples of adaptation. When multiple populations colonize seemingly similar habitats, they may evolve similar genes, traits, or functions.
Barrett, Rowan DH, Bolnick, Daniel I, Oke, Krista B, Rennison, Diana J, Stuart, Yoel E   +4 more
core  

THU0003 CD4+ and B lymphocyte expression quantitative traits at rheumatoid arthritis risk loci in untreated early arthritis: implications for causal gene identification? [PDF]

, 2017
Nishanthi Thalayasingam, Jonathan Massey, AE Anderson, N. Nair, Andrew Skelton, DW Lendrem, Louise N. Reynard, HJ Cordell, Stephen Eyre, Anne Barton, John D. Isaacs, AG Pratt   +11 more
openalex   +1 more source

Genevar: a database and Java application for the analysis and visualization of SNP-gene associations in eQTL studies [PDF]

, 2017
Summary: Genevar (GENe Expression VARiation) is a database and Java tool designed to integrate multiple datasets, and provides analysis and visualization of associations between sequence variation and gene expression.
Beazley, Claude, Deloukas, Panos, Dermitzakis, Emmanouil T., Dimas, Antigone S., Gutierrez-Arcelus, Maria, Montgomery, Stephen B., Stranger, Barbara E., Yang, Tsun-Po   +7 more
core  

Genome-wide association and expression quantitative trait loci studies identify multiple susceptibility loci for thyroid cancer

Nature Communications, 2017
Thyroid cancer is the most common cancer in Korea but previous genome-wide association studies on risk loci have been conducted only in Europeans. Here the authors identify three previously reported loci and seven putatively new loci in the Korean ...
Ho-Young Son, Yul Hwangbo, Seong-Keun Yoo, Sun-Wha Im, San Duk Yang, Soo-Jung Kwak, Min Seon Park, Soo Heon Kwak, Sun Wook Cho, Jun Sun Ryu, Jeongseon Kim, Yuh-Seog Jung, Tae Hyun Kim, Su-jin Kim, Kyu Eun Lee, Do Joon Park, Nam Han Cho, Joohon Sung, Jeong-Sun Seo, Eun Kyung Lee, Young Joo Park, Jong-Il Kim   +21 more
doaj   +1 more source

Leveraging DNA-Methylation Quantitative-Trait Loci to Characterize the Relationship between Methylomic Variation, Gene Expression, and Complex Traits [PDF]

, 2018
Eilís Hannon, T.J. Gorrie-Stone, Melissa Smart, Joe Burrage, Amanda Hughes, Yanchun Bao, Meena Kumari, Leonard C. Schalkwyk, Jonathan Mill   +8 more
openalex   +1 more source

Expression Quantitative Trait Loci (eQTL) mapping for callose synthases in intergeneric hybrids of Citrus challenged with the bacteria Candidatus Liberibacter asiaticus

, 2021
Maiara Curtolo, Laís Moreira Granato, Tatiany Aparecida Teixeira Soratto, Maisa Curtolo, Rodrigo Gazaffi, Marco Aurélio Takita, Mariângela Cristofani–Yaly, Marcos Antônio Machado   +7 more
openalex   +1 more source

Trans-genetic effects of circular RNA expression quantitative trait loci and potential causal mechanisms in autism [PDF]

, 2021
Te‐Lun Mai, Chia-Ying Chen, Tai-Wei Chiang, Trees‐Juen Chuang   +3 more
openalex   +1 more source

Allele-specific NKX2-5 binding underlies multiple genetic associations with human electrocardiographic traits. [PDF]

, 2019
The cardiac transcription factor (TF) gene NKX2-5 has been associated with electrocardiographic (EKG) traits through genome-wide association studies (GWASs), but the extent to which differential binding of NKX2-5 at common regulatory variants contributes
Benaglio, Paola, D'Antonio, Matteo, D'Antonio-Chronowska, Agnieszka, DeBoever, Christopher, Donovan, Margaret KR, Drees, Frauke, Frazer, Kelly A, Gaulton, Kyle J, Li, He, Ma, Wubin, Matsui, Hiroko, Rosenfeld, Michael G, Singhal, Sanghamitra, Smith, Erin N, Sotoodehnia, Nona, van Setten, Jessica, Yang, Feng, Young Greenwald, William W   +17 more
core  

Identification of eQTLs using different sets of single nucleotide polymorphisms associated with carcass and body composition traits in pigs

BMC Genomics
Background Mapping expression quantitative trait loci (eQTLs) in skeletal muscle tissue in pigs is crucial for understanding the relationship between genetic variation and phenotypic expression of carcass traits in meat animals.
Felipe André Oliveira Freitas, Luiz F. Brito, Simara Larissa Fanalli, Janaína Lustosa Gonçales, Bruna Pereira Martins da Silva, Mariah Castro Durval, Fernanda Nery Ciconello, Camila Sabino de Oliveira, Lucas Echevarria Nascimento, Izally Carvalho Gervásio, Julia Dezen Gomes, Gabriel Costa Monteiro Moreira, Bárbara Silva-Vignato, Luiz Lehmann Coutinho, Vivian Vezzoni de Almeida, Aline Silva Mello Cesar   +15 more
doaj   +1 more source