Results 181 to 190 of about 135,054 (291)

Using expression quantitative trait loci data and graph-embedded neural networks to uncover genotype-phenotype interactions. [PDF]

Front Genet, 2022
Guo X, Han J, Song Y, Yin Z, Liu S, Shang X.   +5 more
europepmc   +1 more source

Genetic Mapping of Orofacial Traits Reveals a Single Genomic Region Associated With Differences in Multiple Parameters of Jaw Size Between Astyanax mexicanus Surface and Cavefish

Evolution &Development, EarlyView.
By performing a genetic association study in cave × surface fish F2 hybrids, we discovered that premaxilla width, dentary length, and maxillary length are all significantly associated with a region on Chromosome 13 containing 109 genes. ABSTRACT The regulation of bone size is a poorly understood and complex developmental process.
Amanda K. Powers, Alleigh Amaismeier, Kathryn Thiel, William Anyonge, Suzanne E. McGaugh, Tyler E. Boggs, Clifford J. Tabin, Joshua B. Gross   +7 more
wiley   +1 more source

Trans-genetic effects of circular RNA expression quantitative trait loci and potential causal mechanisms in autism. [PDF]

Mol Psychiatry, 2022
Mai TL, Chen CY, Chen YC, Chiang TW, Chuang TJ.   +4 more
europepmc   +1 more source

Genetic risk factor identification for common epilepsies guided by integrative omics data analysis

Epilepsia, EarlyView.
Abstract Objective Genetic generalized epilepsies (GGEs) comprise the most common genetically determined epilepsy syndromes, following a complex mode of inheritance. Although many important common and rare genetic factors causing or contributing to these epilepsies have been identified in the past decades, many features of the genetic architecture are ...
Ashwini Mushunuri, Oluyomi Adesoji, Roland Krause, Patrick May, Holger Lerche, Albert Becker, Daniela Grimm, International League Against Epilepsy Consortium on Complex Epilepsies, Michael Nothnagel, Herbert Schulz   +9 more
wiley   +1 more source

Role of expression quantitative trait loci (eQTL) in understanding genetic mechanisms underlying common complex diseases. [PDF]

Mol Cells
Hong SE, Choi M, Lee J.
europepmc   +1 more source

Cis -acting expression quantitative trait loci in mice [PDF]

, 2005
Sudheer Doss, Eric E. Schadt, Thomas A. Drake, Aldons J. Lusis   +3 more
openalex   +1 more source

Meta‐analysis of genetic mapping studies in mice reveals candidate epilepsy modifier genes that are outside the current drug development landscape

Epilepsia, EarlyView.
Abstract Objective Despite decades of development in anti‐seizure medications, ~30% of individuals remain refractory to all treatments, and none of the existing therapies are disease modifying. Identifying targets outside the current preclinical paradigm is critically important.
Giovanna L. Durante, Anna L. Tyler, Rod C. Scott, Amanda E. Hernan, J. Matthew Mahoney   +4 more
wiley   +1 more source

Serum microRNA expression quantitative trait loci in children with asthma colocalize with asthma-related GWAS results. [PDF]

NPJ Genom Med
Hecker J, Tiwari A, Sharma R, Mendez K, Li J, Begum S, Chen Q, Smith A, Celedón JC, Weiss ST, Kelly RS, Lasky-Su JA, Tantisira KG, McGeachie M.   +13 more
europepmc   +1 more source

<i>SCFD1</i> expression quantitative trait loci in amyotrophic lateral sclerosis are differentially expressed. [PDF]

Brain Commun, 2021
Iacoangeli A, Fogh I, Selvackadunco S, Topp SD, Shatunov A, van Rheenen W, Al-Khleifat A, Opie-Martin S, Ratti A, Calvo A, UK Brain Expression Consortium , Van Damme P, Robberecht W, Chio A, Dobson RJ, Hardiman O, Shaw CE, van den Berg LH, Andersen PM, Smith BN, Silani V, Veldink JH, Breen G, Troakes C, Al-Chalabi A, Jones AR.   +25 more
europepmc   +1 more source

Hepatitis B virus genotypes, expression quantitative trait loci for ZNRD1-AS1 and their interactions in hepatocellular carcinoma

, 2016
Zhenzhen Liu, Ci Song, Juan Wen, Lu Xu, Yao Liu, Jian Zhu, Liguo Zhu, Zhibin Hu, Hongxia Ma, Li Liu   +9 more
openalex   +2 more sources