Jervell and Lange‐Nielsen Syndrome Related Clinical Genetics and Experimental Models
ABSTRACT Jervell and Lange‐Nielsen syndrome (JLNS) is defined by electrocardiographic QT prolongation and sensorineural hearing loss, caused by homozygous or compound heterozygous variants in KCNQ1 and/or KCNE1. KCNQ1 encodes the alpha subunit Kv7.1 of the ion channels accountable for slow delayed rectifier potassium currents (IKs), whereas KCNE1 ...
Yafei Zhou +3 more
wiley +1 more source
Biodiversity is threatened by human activities, with extinction debt accumulating rapidly. Many of these activities change the connectivity of populations, fragmenting existing population systems or bringing previously isolated populations or species into contact.
Zhiqin Long +7 more
wiley +1 more source
Expression quantitative trait loci associated with performance traits, blood biochemical parameters, and cytokine profile in pigs. [PDF]
Freitas FAO +5 more
europepmc +1 more source
Expression Quantitative Trait Loci (eQTLs) Associated with Retrotransposons Demonstrate their Modulatory Effect on the Transcriptome. [PDF]
Koks S, Pfaff AL, Bubb VJ, Quinn JP.
europepmc +1 more source
Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Mark Rebeiz +9 more
wiley +1 more source
Capsicum chinense as an African traditional vegetable: Culture, resilience, and opportunity
Capsicum chinense is central to everyday diets, cultural identity, and smallholder livelihoods across Sub‐Saharan Africa, yet remains overlooked in agricultural research and policy. This paper reframes C. chinense as a traditional, climate‐resilient vegetable shaped by centuries of farmer stewardship and cultural selection.
Derek W. Barchenger +1 more
wiley +1 more source
Identification and verification of biomarkers associated with neutrophils in acute myocardial infarction: integrated analysis of bulk RNA-seq, expression quantitative trait loci, and mendelian randomization. [PDF]
Liu G +7 more
europepmc +1 more source
From wild to tamed: Reimagining novel crops through omics and local plant diversity
The global food system faces growing pressure from climate change, biodiversity loss, and rising nutritional demands. Agriculture has increased yields but reduced crop diversity, flavor, and nutritional quality, leaving societies vulnerable and dependent on a narrow set of staple species.
Alexandra Sanfeliu Meliá +1 more
wiley +1 more source
Field inoculation with arbuscular mycorrhizal fungi (AMF) offers a promising route to improve sustainable agriculture and food production, yet results are often variable. We investigated the mycorrhizal growth response of maize and wheat varieties recommended for farmers and found substantial variation under greenhouse conditions.
Ido Rog +5 more
wiley +1 more source
Pleiotropic expression quantitative trait loci are enriched in enhancers and transcription factor binding sites and impact more genes. [PDF]
González A, Paul P.
europepmc +1 more source

