Results 111 to 120 of about 251,489 (270)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Extension of the Beta function in several variables and applications for multivariate orthogonal polynomials

Journal of Inequalities and Applications
The fundamental aim of this article is to investigate an extension of the generalized Beta function introduced in (Chaudhry et al. in J. Comput. Appl. Math. 78(1):19–32, 1997) from two variables to three or more variables. The properties of such extended
Nawal Helal Al-harbi, Mustapha Raïssouli   +1 more
doaj   +1 more source

Extended Beta Distribution and Mixture Distributions with applications to Bayesian analysis

, 2013
An extended form of beta distribution by Al-Saleh and Agarwal, is further extended which has an additional two shape parameters k and l. Introduction of new shape parameters help to express extended beta distribution not only as a mixture of ...
A. Al-Saleh, Jamal, K. Agarwal, Satish
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Use of the Extended Fujita method for representing the molecular weight and molecular weight distributions of native and processed oat beta-glucans [PDF]

, 2018
Beta 1–3, 1–4 glucans (“beta-glucans”) are one of the key components of the cell wall of cereals, complementing the main structural component cellulose.
Harding, Stephen E., Grundy, MM - L, Ellis, PR, Adams, GG, Grundy, Myriam M.-L., Harding, SE, Adams, Gary A., Ballance, S, Bajka, Balazs, Grundy, MML, Bajka, B, Butterworth, Peter J., Dinu, Vlad, Ellis, Peter R., Mackie, Alan, Adams, Gary G., Lu, YD, Harding, Stephen E, Channell, Guy A., Gillis, Richard B., Mackie, A, Bajka, Balazs Hendrik; id_orcid, Dinu, V, Butterworth, PJ, Ballance, Simon, Gillis, RB, Lu, Y, Lu, YuDong, Channell, GA, Grundy, Myriam M-L   +29 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

A Wright-Based Generalization of the Euler Beta Function with Statistical Applications

Mathematics
In recent years, special function theory has played an increasingly important role in the development of advanced mathematical models and statistical distributions.
Layth T. Khudhuir, Hiba F. Al-Janaby, Firas Ghanim, Alina Alb Lupaș   +3 more
doaj   +1 more source

Beta Regression in R

The class of beta regression models is commonly used by practitioners to model variables that assume values in the standard unit interval (0, 1). It is based on the assumption that the dependent variable is beta-distributed and that its mean is related ...
Achim Zeileis, Francisco Cribari-Neto
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

\(L^p\)-approximation and generalized growth of generalized biaxially symmetric potentials on hyper sphere

Journal of Numerical Analysis and Approximation Theory, 2018
The generalized order of growth and generalized type of an entire function \(F^{\alpha,\beta}\) (generalized biaxisymmetric potentials) have been obtained in terms of the sequence \(E_n^p(F^{\alpha,\beta},\Sigma_r^{\alpha,\beta})\) of best real ...
Devendra Kumar
doaj   +2 more sources