Results 91 to 100 of about 250,944 (246)

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Certain Extension of the Hurwitz-Lerch Zeta Function and its Properties

مجلّة جامعة عدن للعلوم الأساسيّة والتّطبيقيّة, 2020
The main object of this paper is to introduce a new extension of Hurwitz-Lerch Zeta function by using the extended Beta function given in [1]. Some recurrence relations, generating functions and integral representations are derived for that new extension.
Ahmed Ali Al-Gonah, Waleed Khadher Mohammed   +1 more
doaj  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Extension of the Beta function in several variables and applications for multivariate orthogonal polynomials

Journal of Inequalities and Applications
The fundamental aim of this article is to investigate an extension of the generalized Beta function introduced in (Chaudhry et al. in J. Comput. Appl. Math. 78(1):19–32, 1997) from two variables to three or more variables. The properties of such extended
Nawal Helal Al-harbi, Mustapha Raïssouli   +1 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

An Adaptive Multi-Bernoulli Filter for Coexisting Point Target and Extended Target Tracking With Unknown Detection Probability

IEEE Access
This paper proposes an adaptive multi-Bernoulli (MB) filter for coexisting point target and extended target tracking, where the detection probability of each target is unknown and time-varying. The detection probability of the target directly affects the
Yuansheng Li, Ling Cui, Junhu Ma, Zhaohui Luo   +3 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

\(L^p\)-approximation and generalized growth of generalized biaxially symmetric potentials on hyper sphere

Journal of Numerical Analysis and Approximation Theory, 2018
The generalized order of growth and generalized type of an entire function \(F^{\alpha,\beta}\) (generalized biaxisymmetric potentials) have been obtained in terms of the sequence \(E_n^p(F^{\alpha,\beta},\Sigma_r^{\alpha,\beta})\) of best real ...
Devendra Kumar
doaj   +2 more sources

A Wright-Based Generalization of the Euler Beta Function with Statistical Applications

Mathematics
In recent years, special function theory has played an increasingly important role in the development of advanced mathematical models and statistical distributions.
Layth T. Khudhuir, Hiba F. Al-Janaby, Firas Ghanim, Alina Alb Lupaș   +3 more
doaj   +1 more source