Results 71 to 80 of about 690,349 (272)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Relating Physical Observables in QCD without Scale-Scheme Ambiguity

open access: yes, 1992
We discuss the St\"uckelberg-Peterman extended renormalization group equations in perturbative QCD, which express the invariance of physical observables under renormalization-scale and scheme-parameter transformations.
A. Dhar   +37 more
core   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Power law Kohn anomalies and the excitonic transition in graphene

open access: yes, 2012
Dirac electrons in graphene in the presence of Coulomb interactions of strength $\beta$ have been shown to display power law behavior with $\beta$ dependent exponents in certain correlation functions, which we call the mass susceptibilities of the system.
de Juan, Fernando, Fertig, Herbert A.
core   +1 more source

Nicotinamide riboside functions during development while beta-hydroxybutyrate functions during adulthood to extend C. elegans lifespan

open access: yesmicroPublication biology, 2023
Nicotinamide riboside (NR), a form of vitamin B3 and a nicotinamide adenine dinucleotide (NAD+) precursor, has been shown to activate the mitochondrial unfolded protein response (UPRmt) and extend the lifespan when supplemented to C. elegans. The ketone body and histone deacetylase (HDAC) inhibitor beta-hydroxybutyrate (BHB) has also been shown to ...
Peters, J. Dylan   +2 more
openaire   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

On a Certain Extension of the Hurwitz-Lerch Zeta Function

open access: yesAnnals of the West University of Timisoara: Mathematics and Computer Science, 2014
Our purpose in this paper is to consider a generalized form of the extended Hurwitz-Lerch Zeta function. For this extended Hurwitz-Lerch Zeta function, we obtain some classical properties which includes various integral representations, a differential ...
Parmar Rakesh K., Raina R. K.
doaj   +1 more source

Thermal rounding of the depinning transition in ultrathin Pt/Co/Pt films

open access: yes, 2012
We perform a scaling analysis of the mean velocity of extended magnetic domain walls driven in ultrathin Pt/Co/Pt ferromagnetic films with perpendicular anisotropy, as a function of the applied external field for different film-thicknesses.
A. B. Kolton   +6 more
core   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

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