Results 61 to 70 of about 251,489 (270)
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Functional Dynamics of Substrate Recognition in TEM Beta-Lactamase
The beta-lactamase enzyme provides effective resistance to beta-lactam antibiotics due to substrate recognition controlled by point mutations. Recently, extended-spectrum and inhibitor-resistant mutants have become a global health problem.
Chris Avery +2 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
On a Certain Extension of the Hurwitz-Lerch Zeta Function
Our purpose in this paper is to consider a generalized form of the extended Hurwitz-Lerch Zeta function. For this extended Hurwitz-Lerch Zeta function, we obtain some classical properties which includes various integral representations, a differential ...
Parmar Rakesh K., Raina R. K.
doaj +1 more source
Extende beta, hypergeometric and confluent hypergeometric functions
15 ...
Khan, N. U., Usman, T., Aman, M.
openaire +2 more sources
Continuous correlated beta processes
In this paper we consider a (possibly continuous) space of Bernoulli experiments. We assume that the Bernoulli distributions are correlated. All evidence data comes in the form of successful or failed experiments at different points. Current state-of-the-
Goetschalckx, R., Hoey, J., Poupart, P.
core +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
SOME INEQUALITIES FOR AN EXTENDED BETA FUNCTION [PDF]
M. Raissouli, M. Chergui
openaire +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source

