Results 81 to 90 of about 251,489 (270)

Entropies and Fisher information matrix for extended beta distribution

, 2015
: The extended beta type 1 distribution has the probability density function proportional to x α−1 (1 − x) β−1 exp[−σ/x(1 − x)], 0 < x < 1. In this article, we derive the Fisher information matrix and entropies such as R´enyi and Shannon for the extended
Nagar, Daya Krishna, Sánchez Herrera, Luz Estela, Zarrazola Rivera, Edwin de Jesús   +2 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Visualizing Fractional Integral Inequalities Using Euler’s Beta Function and Extended Convexity

Journal of Applied Mathematics
In this research article, we present various extensions and refinements of Hermite–Hadamard and related fractional integral inequalities by utilizing the unique characteristics of Euler’s beta and extended convex functions.
Muhammad Imran, Ahsan Mehmood, Shahid Mubeen, Muhammad Samraiz, Gauhar Rahman, Mohammad Sediq Safi   +5 more
doaj   +1 more source

Extended precision computation of the incomplete beta function

, 1983
In computing the incomplete beta function, numerical instability is encountered as the parameters increase. To provide a given number of significant digits, a multiple precision (MP) package for the computation of the incomplete beta function has been ...
Ihnen, Leigh
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Some special functions defined by extended beta function

, 2014
Bu tez dört bölümden oluşmaktadır.Birinci bölüm giriş kısmına ayrılmıştır.İkinci bölüm, tezin diğer bölümlerinde kullanılacak olan bazı önbilgileri ve tanımları içermektedir.Üçüncü bölümde, genişletilmiş Beta fonksiyonunun tanımı verilmiştir.
Ayaz, Özlem
core  

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source