From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Determinação fenotípica e genotípica de beta-lactamases de espetro estendido em Escherichia coli, Klebsiella pneumoniae e enterobacter spp. de pacientes internados no Hospital Universitário Professor Polydoro Ernani de São Thiago (HU/UFSC) [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Farmácia, Florianópolis, 2014.As enterobactérias são patógenos oportunistas responsáveis por cerca de 70% das infecções urinárias e
Zamparette, Caetana Paes
core
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Extended precision computation of the incomplete beta function
In computing the incomplete beta function, numerical instability is encountered as the parameters increase. To provide a given number of significant digits, a multiple precision (MP) package for the computation of the incomplete beta function has been developed. Since MP arithmetic is time consuming, finding an efficient algorithm is important.
openaire +2 more sources
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
A note on the generalized ML function as the kernel of the extended wright function
This paper introduces a unified generalization of the Gamma and Beta functions by employing the generalized Mittag-Leffler function as the kernel.
Pallavi Sharma +5 more
doaj +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Certain Extension of the Hurwitz-Lerch Zeta Function and its Properties
The main object of this paper is to introduce a new extension of Hurwitz-Lerch Zeta function by using the extended Beta function given in [1]. Some recurrence relations, generating functions and integral representations are derived for that new extension.
Ahmed Ali Al-Gonah +1 more
doaj
ON EXTENSIONS OF EXTENDED BETA AND GAUSS HYPERGEOMETRIC FUNCTIONS WITH THEIR APPLICATIONS
The Beta function and its extensions play a crucial role in the study of some special functions; several researchers have introduced and investigated various extensions of this important function. In this paper we present further extensions of the Beta and the Gauss hypergeometric functions.
M. A. H Kulib, F. B. F. Mohsen
openaire +1 more source
Adler-Bardeen theorem and vanishing of the gauge beta function
The proof of the non-renormalization theorem for the gauge anomaly of four-dimensional theories is extended to the case of models with a vanishing one-loop gauge beta ...
Piguet, Olivier, Sorella, Silvio Paolo
core +1 more source

