Results 61 to 70 of about 113,287 (282)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Extended Mind Thesis and Quantum Cognition
, 2023 The Extended Mind Thesis holds that mental states are realized in extended physical systems and are not identical with processes occurring inside the brain.
Navjot Singh
core +1 more source
Five Major Ethical Issues Concerning Extended Cognitive Technology
Contemporary Social Sciences, 2017 Extended cognitive technology refers to technology that extends cognitive activity from the human brain, or body, to an external cognitive environment. This technology is best represented by the Internet. While significantly benefiting humanity and
Song Chunyan
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Defending extended cognition [PDF]
, 2007 In this paper, we defend extended cognition against several criticisms. We argue that extended cognition does not derive from armchair theorizing and that it neither ignores the results of the neural sciences, nor minimizes the importance of the brain in
Anthony Chemero +3 more
core +2 more sources
CONSTRUCTING RELIGION WITHOUT THE SOCIAL: DURKHEIM, LATOUR, AND EXTENDED COGNITION
Zygon, 2009 I take up the question of how models of extended cognition might redirect the academic study of religion. Entering into a conversation of sorts with Emile Durkheim and Bruno Latour regarding the “overtakenness” of social agency, I argue that a robust ...
doaj +2 more sources
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Plant agency: from senome and electrome to plant semiosphere
Frontiers in Plant PhysiologyHistorically constrained by mechanistic and cerebrocentric paradigms, plant life is increasingly recognized as a complex expression of biological agency.
Luís Felipe Basso +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source