Results 81 to 90 of about 113,287 (282)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
, 2010 Whereas the traditional view in cognitive science has been to view mind and cognition as something that is the result of essentially inner, neural processes, the extended cognition perspective claims that at least some human mental states and processes ...
Engelbrecht, Paula C +4 more
core
Transparency and the phenomenology of extended cognition [PDF]
, 2020 Extended cognition brings with it a particular phenomenology. It has been argued that when an artifact is integrated into an agent’s cognitive system, it becomes transparent in use to the cognizing subject.
Andrada, Gloria
core +3 more sources
IEEJ Transactions on Electronics, Information and Systems, 1994 Fuzzy cognitive maps (FCMs) have been proposed to represent causal reasoning by using numeric processing. They graphically represent uncertain causal reasoning. In the resonant states, there emerges a limit cycle or a hidden pattern, which is a FCM inference.
openaire +2 more sources
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Are There Any Situated Cognition Concepts of Memory Functioning as Investigative Kinds in the Sciences of Memory? [PDF]
, 2015 This thesis will address the question of whether there are any situated cognition concepts of memory functioning as investigative kinds in the sciences of memory. Situated cognition is an umbrella term, subsuming extended, embedded, embodied, enacted and
Hibbert, Ruth
core
Inference to the hypothesis of extended cognition
Studies in History and Philosophy of Science Part A, 2010 Abstract This paper examines the justification for the hypothesis of extended cognition (HEC). HEC claims that human cognitive processes can, and often do, extend outside our head to include objects in the environment. HEC has been justified by inference to the best explanation (IBE).
openaire +2 more sources
Extended cognition and humility [PDF]
, 2020 Extended cognition is when cognitive processes extend beyond the brain and nervous system of the subject, and in the process properly include such ‘external’ devices as technology. This paper explores what relevance extended cognitive processes might have for humility, and especially for the specifically cognitive aspect of humility—viz., intellectual ...
openaire +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source