Results 51 to 60 of about 1,601,477 (275)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Penetration of non-uniform electromagnetic field into conducting body

Electrical engineering & Electromechanics, 2021
The study is based on the exact analytical solution for the general conjugation problem of three-dimensional quasi-stationary field at a flat interface between dielectric and conducting media.
Yu. M. Vasetsky
doaj   +1 more source

Dynamics of cold bosons in optical lattices: Effects of higher Bloch bands [PDF]

, 2012
The extended effective multiorbital Bose-Hubbard-type Hamiltonian which takes into account higher Bloch bands, is discussed for boson systems in optical lattices, with emphasis on dynamical properties, in relation with current experiments.
Bissbort U Deuretzbacher F Hofstetter W, Clark S R, Dominique Delande, Dutta O, Fermi E, Freericks J K, Gubbels K B, Jakub Zakrzewski, Johnson P R, Lewenstein M, Lühmann D S, Mateusz Łącki, Rontani M Åberg S Reimann S M, Sakmann K, Verstraete F Cirac J I, Łącki M   +15 more
core   +4 more sources

Optical/digital incoherent image processing for extended depth of field [PDF]

Applied Optics, 1987
For a severely defocused incoherent system, its optical transfer function (OTF) has isolated zeros; therefore, an exact inverse filtering cannot be performed. Isolated zeros in the OTF can be avoided by choosing an annular aperture with a proper radius ratio, as the aperture can extend the depth of focus of the system.
Poon, Ting-Chung, Motamedi, M.
openaire   +3 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Implantation of diffractive extended depth-of-focus intraocular lenses in normal tension glaucoma eyes: A case series

American Journal of Ophthalmology Case Reports, 2023
Purpose: Implantation of presbyopia-correcting intraocular lenses (IOLs) has not been advised for glaucomatous eyes because of the risk of decreased contrast sensitivity with progress of glaucoma.
Hiroko Bissen-Miyajima, Yuka Ota, Kenya Yuki, Keiichiro Minami   +3 more
doaj   +1 more source

On space efficiency of algorithms working on structural decompositions of graphs [PDF]

, 2016
Dynamic programming on path and tree decompositions of graphs is a technique that is ubiquitous in the field of parameterized and exponential-time algorithms.
Pilipczuk, Michał, Wrochna, Marcin
core   +2 more sources

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source