Results 91 to 100 of about 2,666,458 (257)

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Nic o nas bez nas [okładka płyty z tekstami piosenek

, 2007
Skład zespołu: Paweł „Anzelm” Dubaniewicz – perkusja, Mariusz „Żuber” Kozak-Sikorski - bas, Paweł ”Pakos” Peresada - gitara, Skład zespołu: Paweł „Anzelm” Dubaniewicz – perkusja, Mariusz „Żuber” Kozak-Sikorski - bas, Paweł ”Pakos” Peresada - gitara ...
wykonawca Back to Reality
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Technologically Modified Self–Centred Worlds. Modes of Presence as Effects of Sense in Virtual, Augmented, Mixed and Extended Reality

, 2020
The paper aims to consider different forms of extended reality (virtual, augmented and mixed reality) as manifestations of “technologically modified self–centered worlds (Umwelte)”.
Eugeni, R., Catricala, Valentino, Eugeni, Ruggero   +2 more
core  

A Mixed Presence Collaborative Mixed Reality System

, 2019
Research has shown that Mixed Presence Groupware (MPG) systems are a valuable collaboration tool. However research into MPG systems is limited to a handful of tabletop and Virtual Reality (VR) systems with no exploration of Head-Mounted Display (HMD ...
Lee, G., Gun Lee, Smith, R.T., Ross T. Smith, Mitchell Norman, Norman, M., Mark Billinqhurs, Billinqhurs, M.   +7 more
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Diegetic User Interfaces in Extended Reality for 3D Medical Visualization

The integration of 3D anatomical models derived from DICOM images into extended reality (XR) interfaces significantly enhances the visualization and interaction with anatomical data, particularly in educational, pre-operative, and intra-operative medical
Loretti A., Cascarano P., Vallasciani G., Hajahmadi S., Di Pasquale A., Marfia G., Zanuttini L., Martinoni M.   +7 more
core   +1 more source

Extended Reality for Midwifery Learning: MR VR Demonstration

, 2019
This demonstration presents a development of a Mixed Reality (MR) and Virtual Reality (VR) research project for midwifery student learning, and a novel approach for showing extended reality content in an educational setting.
Lizbeth Goodman, Zi Siang See, Billinghurst, M., Donovan Jones, Goodman, L., Mark Billinghurst, Shanna Fealy, See, Z.S., Fealy, S., Jones, D.   +9 more
core   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source