IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Challenges and Opportunities for Theory-Grounded Data Visualization in Extended Reality. [PDF]
Bueckle A +9 more
europepmc +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
Extended Reality in Rehabilitation Medicine: A Systematic Review. [PDF]
Hao J, Yao Y, Siu KC.
europepmc +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
The Use of Extended Reality Distraction Methods During Needle-Related Procedures in Pediatric Hospital Care-Children's Experiences. [PDF]
Stålberg A +3 more
europepmc +1 more source
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
X-NR: Towards An Extended Reality-Driven Human Evaluation Framework for Neural-Rendering
The joint usage of Extended Reality (XR) and Artificial Intelligence (AI) has enabled different Metaverse-related use cases. Such paradigms were recently adopted for immersive content creation, particularly considering Neural Rendering (NR) techniques to
Pierdicca, Roberto +5 more
core +1 more source
Editorial: Reimagining human movement: the impact of extended reality on physical and emotional experience. [PDF]
Ramalho A +3 more
europepmc +1 more source

