Results 41 to 50 of about 196,185 (255)

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Gauge fixing, BRS invariance and Ward identities for randomly stirred flows [PDF]

, 2009
The Galilean invariance of the Navier-Stokes equation is shown to be akin to a global gauge symmetry familiar from quantum field theory. This symmetry leads to a multiple counting of infinitely many inertial reference frames in the path integral approach
Abers, Adzhemyan, Arjun Berera, Balkovsky, Balkovsky, Becchi, Becchi, Berera, Berera, Bjorken, David Hochberg, De Dominicis, DeDominicis, DeDominicis, Düben, Eyink, Forster, Homeier, Ivashkevich, Janssen, Jensen, Kardar, Lebedev, Martin, McComb, McComb, Mou, Phythian, Pokorski, Pope, Ramond, Shah, Teodorovich, Tomassini, Tong, Weinberg, Zinn-Justin   +36 more
core   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Population oscillations in spatial stochastic Lotka-Volterra models: A field-theoretic perturbational analysis

, 2012
Field theory tools are applied to analytically study fluctuation and correlation effects in spatially extended stochastic predator-prey systems. In the mean-field rate equation approximation, the classic Lotka-Volterra model is characterized by neutral ...
Tauber, Uwe C.
core   +1 more source

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig, Nadav Amir, Maya Schiller, Roni Loebenstein, Johnatan Nissan, Marina Boxer, Shany Guly Gofrit, Gal Goshen, Sándor Beniczky, Nicola Maggio   +9 more
wiley   +1 more source

Peano Theorems for Pedjeu–Ladde-Type Multi-Time Scale Stochastic Differential Equations Driven by Fractional Noises

Mathematics
This paper examines fractional multi-time scale stochastic functional differential equations that, in addition, are driven by fractional noises. Based on a specially crafted fixed-point principle for the so-called “local operators”, we prove a Peano-type
Arcady Ponosov, Lev Idels
doaj   +1 more source

Averaged residence times of stochastic motions in bounded domains [PDF]

, 2005
Two years ago, Blanco and Fournier (Blanco S. and Fournier R., Europhys. Lett. 2003) calculated the mean first exit time of a domain of a particle undergoing a randomly reoriented ballistic motion which starts from the boundary.
Bénichou O., Bénichou O., Gardiner C. W., Hughes B. D., Kac M., M Coppey, M Moreau, O Bénichou, P. H Suet, R Voituriez, Risken H., Van Kampen N. G., Weiss G. H.   +12 more
core   +1 more source

Characterization of Defect Distribution in an Additively Manufactured AlSi10Mg as a Function of Processing Parameters and Correlations with Extreme Value Statistics

Advanced Engineering Materials, EarlyView.
Predicting extreme defects in additive manufacturing remains a key challenge limiting its structural reliability. This study proposes a statistical framework that integrates Extreme Value Theory with advanced process indicators to explore defect–process relationships and improve the estimation of critical defect sizes. The approach provides a basis for
Muhammad Muteeb Butt, Varma Kvvssn, Hossein Laieghi, Zia Uddin, Peyman Ansari, E. Kıvanç Sadak, Can Barış Toprak, Hüseyin Kızıl, Enrico Salvati   +8 more
wiley   +1 more source

A Multi-Sensor Fusion MAV State Estimation from Long-Range Stereo, IMU, GPS and Barometric Sensors

Sensors, 2016
State estimation is the most critical capability for MAV (Micro-Aerial Vehicle) localization, autonomous obstacle avoidance, robust flight control and 3D environmental mapping.
Yu Song, Stephen Nuske, Sebastian Scherer   +2 more
doaj   +1 more source

Stochastic Analysis of Gaussian Processes via Fredholm Representation [PDF]

, 2016
We show that every separable Gaussian process with integrable variance function admits a Fredholm representation with respect to a Brownian motion. We extend the Fredholm representation to a transfer principle and develop stochastic analysis by using it.
Sottinen, Tommi, Viitasaari, Lauri
core   +2 more sources