Results 101 to 110 of about 1,523,478 (287)
Insights into a long life without cancer: The case of the bowhead whale
Molecular Oncology, EarlyView.Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley +1 more source
Ain Shams Engineering JournalThis study presents a framework for addressing the fuzzy fractional three-stage transportation network (FFTSTN) in the context of sustainable conveyance.
B. Baranidharan +3 more
doaj +1 more source
Heuristics of the General Relativity [PDF]
The general theory of relativity was developed using as a nucleus a principle of symmetry: the principle of general covariance. Initially, Einstein saw the principle of general covariance as an extension of the principle of relativity in classical ...
Sfetcu, Nicolae
core
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
Variational Principle for Relative Tail Pressure
Entropy, 2017 We introduce the relative tail pressure to establish a variational principle for continuous bundle random dynamical systems. We also show that the relative tail pressure is conserved by the principal extension.
Xianfeng Ma, Ercai Chen
doaj +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Leibniz's Principles and Topological Extensions
, 2010 Three philosophical principles are often quoted in connection with Leibniz: "objects sharing the same properties are the same object", "everything can possibly exist, unless it yields contradiction", "the ideal elements correctly determine the real things".
openaire +2 more sources
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Classical Correspondence of Squeezing Operators and the Extension of Bohr’s Correspondence Principle
PhotonicsBohr’s correspondence principle acts as a link between quantum physics and classical physics theory, while squeezed light, as a special nonclassical quantum state in quantum physics, achieves precision measurements and gravitational wave detection by ...
Ke Zhang, Hongyi Fan
doaj +1 more source