Results 171 to 180 of about 2,978,826 (285)

Limb salvage in diabetic foot necrotizing fasciitis complicated by extensively drug-resistant <i>Acinetobacter baumannii</i>: a case report of an integrative treatment approach. [PDF]

Front Endocrinol (Lausanne)
Tian Y, Shi Y, Liu P, Xu Q, Zhang C, Zhang Y.   +5 more
europepmc   +1 more source

Inhibition of VEGF‐Induced Angiogenesis and Vascular Leakage by Bicistronic Co‐Expression of Aflibercept and COMP‐Ang1

Advanced Healthcare Materials, EarlyView.
A bicistronic rAAV8 vector encoding Aflibercept (Afb) and COMP‐cAng1 simultaneously coordinates VEGF clearance and Tie2‐mediated vessel maturation. In a 3D angiogenesis‐on‐a‐chip model, rAAV8‐Afb/cAng1 effectively reverses pathological barrier breakdown under clinical disease‐mimicking challenges.
Bong‐Kyu Kim, Jaehong Min, Sang‐Hee Park, Subeen Shin, Sangbin Yu, Jeong‐Eun Park, Sujin Kim, Wooju Park, Jihoon Ko, Sunjong Kwon   +9 more
wiley   +1 more source

Extensively Drug-Resistant Tuberculosis, Central China, 2007–2009

Emerging Infectious Diseases, 2012
Dawei Shi, Hui Li, Yuling Zhao, Qiong Jia, Christopher Coulter, Liang Li, Guofeng Zhu   +6 more
doaj   +1 more source

Burden of multidrug-resistant and extensively drug-resistant tuberculosis in China, India and Russia: estimates from the GBD 2023 study. [PDF]

J Thorac Dis
Li JD, Li ZY, Xiong KH, Ling JW, Chen GQ, Tang HH, Huang BB, Chen YT, Chen G, Ning Z, Feng H.   +10 more
europepmc   +1 more source

Mitochondria‐Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave, Ashish B. Jadhav, Nitin B. Waghamode, Shubham Khot, Rajiya Khan, Ravi Hole, Shankar M. Dhobale, Manoj Aswar, Keshav Raj Paudel   +8 more
wiley   +1 more source

Escalation of CTX-M-producing extensively drug-resistant <i>Shigella</i> spp. in Kolkata, India, following the COVID-19 pandemic. [PDF]

Microbiol Spectr
Bose P, Halder G, Kayet P, Chowdhury G, Basak S, Roy D, Imamura D, Miyoshi S-i, Morita M, Ramamurthy T, Koley H, Das S, Mukhopadhyay AK.   +12 more
europepmc   +1 more source

Tumor‐Targeted Hyaluronic Acid/Tannic Acid‐Engineered Oxygen Nanogenerators With IR780 Payloads Enable Dual‐Mode Glutathione Depletion and Effective Singlet Oxygen Generation for Melanoma Treatment

Advanced Healthcare Materials, EarlyView.
A hyaluronic acid/tannic acid‐engineered Prussian blue oxygen nanogenerator loaded with IR780 is developed to enhance melanoma phototherapy. By integrating tumor targeting, oxygen self‐supply, and dual‐mode glutathione depletion, the nanoplatform effectively overcomes hypoxia and antioxidant defenses, potentiating synergistic photothermal/photodynamic ...
Chai‐How Hsu, I‐Ju Liu, Hsiang‐Yun Chih, Tsai‐Ching Hsu, Ju‐An Liang, Chia‐Wei Kuo, Bor‐Show Tzang, Wen‐Hsuan Chiang   +7 more
wiley   +1 more source

Integron architecture and virulence-associated gene profiles in extensively drug-resistant high-risk <i>Pseudomonas aeruginosa</i> ST309 and ST233. [PDF]

Front Microbiol
Fernández-Vázquez JL, Jarillo-Quijada MD, Castillo-Ramírez S, Hernández-Medel ML, Zavala-Pineda M, Osorio-Guzmán M, Santos-Preciado JI, Alcántar-Curiel MD.   +7 more
europepmc   +1 more source

Overcoming Photodynamic Therapy Resistance: GSH‐Responsive AIE Photosensitizer‐Hydroxycamptothecin Nanoliposomes for Extrahepatic Cholangiocarcinoma

Advanced Healthcare Materials, EarlyView.
A GSH‐responsive AIE nanoplatform (TSH NPs) with RGD‐mediated tumor targeting co‐delivers a photosensitizer (TPA) and HCPT for extrahepatic cholangiocarcinoma. The system synergistically enhances PDT and chemotherapy by suppressing HIF‐1α/VEGF‐driven hypoxic adaptation, effectively overcoming PDT resistance.
Yong Qu, Tao Peng, Yating Zhang, Juanmei Cao, Birong Wang, Chuxing Chai, Zhiyuan Gao, Yiting Xu, Yifan Jin, Yuqing Wang, Zhuoxia Li, Xu Liu, Tianqi Zhao, Yufan Chen, Weimin Lv, Di Lu, Changzheng Huang, Dan Ding, Jinxiang Zhang, Min Li   +19 more
wiley   +1 more source

Antimicrobial-laden PerOssal beads display in vitro inhibition and killing of extensively drug-resistant Gram-negative bacteria associated with conflict wounds in Ukraine. [PDF]

Bone Joint Res
Claireaux HA, Douglas EJA, Pallett SJC, Moore LSP, O'Shea MK, Moshynets OV, Jones JR, Ramasamy A, Edwards AM.   +8 more
europepmc   +1 more source