Results 201 to 210 of about 23,332 (236)
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Extensively Drug-resistant Tuberculosis

The American Journal of Medicine, 2008
Extensively drug-resistant tuberculosis (XDR-TB) is defined as Mycobacterium tuberculosis infection that is resistant to isoniazid, rifampin, any fluoroquinolone, and any injectable drug (amynoglicosides or polypetides). Although initially described in South Africa, it has emerged as a global threat, and cases have been reported from several countries,
Miguel G, Madariaga   +2 more
  +8 more sources

Multi-Drug Resistant and Extensively-Drug Resistant Tuberculosis

The Indian Journal of Pediatrics, 2020
India is one of the high burden countries for tuberculosis (TB) including multi-drug resistant TB (MDR-TB) and extensively-drug resistant (XDR) TB. Drug-resistant (DR) TB has threatened the TB care and is a major health problem in many countries; treatment of DR TB has been difficult requiring use of reserve or second-line drugs, cost factors, has ...
Ira, Shah   +2 more
openaire   +2 more sources

Cutaneous Extensively Drug-Resistant Tuberculosis

The American Journal of Tropical Medicine and Hygiene, 2007
A 48-year-old immunocompetent man without known exposure to tuberculosis had a > 10-year history of recurrent skin lesions. Cutaneous tuberculosis without any current or past history of pulmonary tuberculosis was diagnosed. Culture of biopsy specimens showed the organism to be resistant to multiple first-line and second-line agents.
Douglas P, Olson   +4 more
openaire   +2 more sources

Multidrug and extensively drug-resistant tuberculosis

Médecine et Maladies Infectieuses, 2017
The emergence of drug-resistant tuberculosis (TB) compromises global tuberculosis control. The incidence of multidrug-resistant strains (MDR) defined as resistant to the two main antituberculosis drugs, rifampicin and isoniazid, was raised in the 1990s.
Maitre, Thomas   +10 more
openaire   +4 more sources

Controlling extensively drug-resistant tuberculosis

The Lancet, 2007
Recent successes in the fight against tuberculosis rely on short-course chemotherapy with our two most powerful drugs isoniazid and rifampicin. Unfortunately not only do hundreds of thousands of people or more still die every year of curable tuberculosis1 but inadequate treatment has also contributed to the origination of strains of tuberculosis ...
Travis C, Porco, Wayne M, Getz
openaire   +2 more sources

Linezolid in the treatment of extensively drug-resistant tuberculosis

Infection, 2014
To investigate the linezolid (LZD) treatment outcome and correlation between in vitro susceptibility to LZD and clinical outcome.We retrospectively reviewed records of tuberculosis (TB) patients who received treatment with linezolid between March 2012 and February 2013.A total of 43 extensively drug-resistant (XDR) TB patients identified by drug ...
L, Zhang   +6 more
openaire   +2 more sources

Predictors of Extensively Drug-Resistant Pulmonary Tuberculosis

Annals of Internal Medicine, 2009
About 40 000 cases of extensively drug-resistant tuberculosis emerge worldwide annually, but the predictors of extensive drug resistance are unclear.To identify risk factors for extensively drug-resistant tuberculosis and multidrug-resistant but non-extensively drug-resistant tuberculosis in patients with culture-confirmed pulmonary tuberculosis.Cross ...
Kai, Kliiman, Alan, Altraja
openaire   +2 more sources

Drug-resistant and extensively drug-resistant tuberculosis in southern Africa

Current Opinion in Pulmonary Medicine, 2010
Drug-resistant tuberculosis (TB) is of increasing global concern. One of the hardest hit regions is southern Africa. This study focuses on a concise update on recently published developments in the field.There is mounting evidence from high-coprevalence areas that the TB and HIV pandemics must be viewed as an entity and tackled together.
openaire   +3 more sources

Extensively Drug-resistant Tuberculosis: Epidemiology and Management Challenges

Infectious Disease Clinics of North America, 2010
Widespread global use of rifampin for 2 decades preceded the emergence of clinically significant multidrug-resistant tuberculosis (MDR-TB) in the early 1990s. The prevalence of MDR-TB has gradually increased such that it accounts for approximately 5% of the global case burden of disease (approximately half a million cases in 2007).
Dheda, Keertan   +3 more
openaire   +2 more sources

Extensively Drug-Resistant Tuberculosis

2014
It has been many years since a single agent was recommended for treatment of active tuberculosis (TB). Despite this, there is strong evidence that multidrug-resistant TB (MDR-TB) and extensively drug-resistant TB (XDR-TB) are present in all regions of the world, and there is also evidence that the incidence of drug-resistant forms of TB is increasing ...
openaire   +1 more source

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