Results 91 to 100 of about 2,979,111 (255)

Successful Treatment of Extensively Drug-Resistant Acinetobacter baumannii Intracranial Infection with Meropenem and Cefoperazone Sodium Sulbactam: A Case Report [PDF]

Wenke Ma,1 Chao Zhang,1 Bei He,1 Xinwen Lv,1 Peng Luo2 1Department of Neurosurgery, Baoji Central Hospital, Baoji, Shaanxi, People’s Republic of China; 2Department of Neurosurgery, The First Affiliated Hospital of Air Force Medical University, Xi’an ...
Luo P, Lv X, Zhang C, He B, Ma W
core  

Risk Factors, Outcomes, and Predictions of Extensively Drug-Resistant Acinetobacter baumannii Nosocomial Infections in Patients with Nervous System Diseases

, 2023
Li Huang,1– 3,* Jingyang Tang,1– 3,* Gang Tian,1– 3 Hualin Tao,1– 3 Zhaoyinqian Li1– 3 1Department of Laboratory Medicine, the Affiliated Hospital of Southwest Medical University, Luzhou, People’s Republic of China; 2Sichuan Province Engineering ...
Tang J, Li Z, Tian G, Tao H, Huang L
core  

Prevalence of Extensively Drug-Resistant Tuberculosis: a Descriptive Study

Эпидемиология и вакцинопрофилактика, 2018
Background. Extensively drug-resistant tuberculosis (XDR-TB) is a threat to community health. Goal. The estimation of the prevalence of extensively drug-resistant tuberculosis in Omsk region, along with the clinical and epidemiological description of ...
O. A. Pasechnik, A. A. Zimoglyad, I. V. Yarusova, S. V. Vitriv, A. I. Blokh   +4 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Moxifloxacin resistance in the F15/LAM4/KZN extensively drug-resistant strain of Mycobacterium tuberculosis

, 2014
Navisha Dookie, A Willem Sturm, Prashini Moodley Department of Infection Prevention and Control, Nelson R Mandela School of Medicine, School of Laboratory Medicine and Medical Science, College of Health Science, University of KwaZulu-Natal, Durban, South
Dookie N, Sturm AW, Moodley P
core  

Distribution of Extensively Drug-resistant Tuberculosis in the World Health Organization Regions of the World During 1990-2019 [PDF]

The rise of drug-resistant tuberculosis (TB) has become a significant public health concern, representing a threat to global TB control programs. Extensively drug-resistant TB (XDR-TB) accounts for approximately 9% of all drug-resistant cases, and its ...
Maryam KAZEMI, Marzieh MAHMUDIMANESH, Bagher MORADI, Moslem Taheri SOODEJANI   +3 more
core   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Extensively Drug-Resistant (XDR) Enteric Fever in Children

Pakistan Journal of Medicine and Dentistry
Background: Typhoid and paratyphoid fevers are caused by Salmonella enterica subspecies serovars typhi (Salmonella typhi and Paratyphi) and the term enteric fever is generally used to describe both.
Sana Ashraf , Mehtab Hussain, Asma Noreen, Falak Abro, Nadeem Noor, Ramla Rehman   +5 more
doaj   +1 more source

Resistance to Second-Line Anti-TB Drugs in Cambodia: A Phenotypic and Genetic Study

Infection and Drug Resistance, 2021
Sokleaph Cheng,1– 3 Mallorie Hide,3– 5 Sok Heng Pheng,6 Alexandra Kerléguer,2 Gauthier Delvallez,2 Sophan Sam,7 Tan Eang Mao,6 Thi Van Anh Nguyen,3,8 Anne-Laure Bañuls3– 5 1Institut Pasteur du Cambodge and Ministry of ...
Cheng S, Hide M, Pheng SH, Kerléguer A, Delvallez G, Sam S, Mao TE, Nguyen TVA, Bañuls AL   +8 more
doaj