Results 161 to 170 of about 4,965 (214)
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
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Journal of Hand Surgery, 2010
The extensor mechanism of the fingers, hand, wrist, and forearm is extremely intricate. Disruptions to the extensor system are common and can be associated with poor patient outcomes when not treated appropriately. Although extensor tendon injuries receive much less attention in the literature than flexor tendon injuries do, several recent studies have
Jonas L, Matzon, David J, Bozentka
exaly +3 more sources
The extensor mechanism of the fingers, hand, wrist, and forearm is extremely intricate. Disruptions to the extensor system are common and can be associated with poor patient outcomes when not treated appropriately. Although extensor tendon injuries receive much less attention in the literature than flexor tendon injuries do, several recent studies have
Jonas L, Matzon, David J, Bozentka
exaly +3 more sources
Hand Surgery and Rehabilitation, 2020
We aimed to investigate tendon variations of the extensor digitorum (ED), extensor digiti minimi (EDM), and extensor indicis proprius (EIP) muscles. Our study was performed on 43 fetal cadavers (86 extremities), aged between 17 and 40 weeks of gestation.
ALBAY, Soner +3 more
openaire +4 more sources
We aimed to investigate tendon variations of the extensor digitorum (ED), extensor digiti minimi (EDM), and extensor indicis proprius (EIP) muscles. Our study was performed on 43 fetal cadavers (86 extremities), aged between 17 and 40 weeks of gestation.
ALBAY, Soner +3 more
openaire +4 more sources
Failed Extensor Tendon Repairs: Extensor Tenolysis and Reconstruction
Journal of the American Academy of Orthopaedic Surgeons, 2019Extensor tendon injuries are common and require a complex treatment strategy to appropriately manage them, including initial repair, revision/reconstruction options, and postoperative protocols. Intrinsic and extrinsic components of the extensor mechanism contribute to a complex anatomic apparatus but also allow for numerous reconstructive options ...
Mihir J, Desai +3 more
openaire +2 more sources
Clinics in Sports Medicine, 2015
Extensor mechanism injuries are frequently encountered in athletes and can lead to permanent disability or deformity if not promptly and properly treated. This article reviews basic anatomy, and then discusses mallet finger injuries, boutonniere deformity, and sagittal band rupture.
John T, McMurtry, Jonathan, Isaacs
openaire +2 more sources
Extensor mechanism injuries are frequently encountered in athletes and can lead to permanent disability or deformity if not promptly and properly treated. This article reviews basic anatomy, and then discusses mallet finger injuries, boutonniere deformity, and sagittal band rupture.
John T, McMurtry, Jonathan, Isaacs
openaire +2 more sources
Proceedings of the 52nd Annual IEEE/ACM International Symposium on Microarchitecture, 2019
Generalized tensor algebra is a prime candidate for acceleration via customized ASICs. Modern tensors feature a wide range of data sparsity, with the density of non-zero elements ranging from 10-6% to 50%. This paper proposes a novel approach to accelerate tensor kernels based on the principle of hierarchical elimination of computation in the presence ...
Kartik Hegde +7 more
openaire +1 more source
Generalized tensor algebra is a prime candidate for acceleration via customized ASICs. Modern tensors feature a wide range of data sparsity, with the density of non-zero elements ranging from 10-6% to 50%. This paper proposes a novel approach to accelerate tensor kernels based on the principle of hierarchical elimination of computation in the presence ...
Kartik Hegde +7 more
openaire +1 more source
Plastic and Reconstructive Surgery, 1993
This is the first reported case in the literature of an extra extensor muscle and tendon to the right thumb. It was discovered during routine dissection of a male cadaver. The muscle originated from the dorsal surface of the lower third of the ulna immediately proximal to the origin of the extensor indicis proprius.
openaire +2 more sources
This is the first reported case in the literature of an extra extensor muscle and tendon to the right thumb. It was discovered during routine dissection of a male cadaver. The muscle originated from the dorsal surface of the lower third of the ulna immediately proximal to the origin of the extensor indicis proprius.
openaire +2 more sources