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JAHEE external evaluation [PDF]

Eur J Public Health, 2022
Abstract The general aims and evaluation blocks concerned the extent to which JAHEE achieved its objectives, and the identification of lessons learned for future health inequalities programmes. More specific aims included: • Producing knowledge: to understand the outcomes of JAHEE and build knowledge on health inequalities. • Influencing
Balaj M.
europepmc   +2 more sources

External Evaluation of Population Pharmacokinetic Models of Busulfan in Chinese Adult Hematopoietic Stem Cell Transplantation Recipients [PDF]

Frontiers in Pharmacology, 2022
Objective: Busulfan (BU) is a bi-functional DNA-alkylating agent used in patients undergoing hematopoietic stem cell transplantation (HSCT). Over the last decades, several population pharmacokinetic (pop PK) models of BU have been established, but ...
Huiping Huang, Huiping Huang, Qingxia Liu, Qingxia Liu, Xiaohan Zhang, Helin Xie, Maobai Liu, Nupur Chaphekar, Xuemei Wu   +8 more
doaj   +2 more sources

External evaluation of published population pharmacokinetic models of posaconazole [PDF]

Frontiers in Pharmacology, 2022
Population pharmacokinetic (PopPK) models of posaconazole have been established to promote the precision dosing. However, the performance of these models extrapolated to other centers has not been evaluated.
Shuqi Huang, Qin Ding, Nan Yang, Zexu Sun, Qian Cheng, Wei Liu, Yejun Li, Xin Chen, Cuifang Wu, Qi Pei   +9 more
doaj   +2 more sources

External Evaluation of Population Pharmacokinetic Models to Inform Precision Dosing of Meropenem in Critically Ill Patients [PDF]

Frontiers in Pharmacology, 2022
Routine clinical meropenem therapeutic drug monitoring data can be applied to model-informed precision dosing. The current study aimed to evaluate the adequacy and predictive capabilities of the published models with routine meropenem data and identify ...
Nan Yang, Jing Wang, Yueliang Xie, Junjie Ding, Cuifang Wu, Jingjing Liu, Qi Pei   +6 more
doaj   +2 more sources

External Evaluation of Population Pharmacokinetics Models of Lithium in the Bipolar Population [PDF]

Pharmaceuticals, 2023
Lithium has been used in the treatment of bipolar disorder for several decades. Treatment optimization is recommended for this drug, due to its narrow therapeutic range and a large pharmacokinetics (PK) variability.
Lereclus Aurélie, Boniffay Andréa, Kallée Gauvind, Blin Olivier, Belzeaux Raoul, Frédéric Dayan, Benito Sylvain, Guilhaumou Romain   +7 more
doaj   +2 more sources

Published population pharmacokinetic models of mycophenolate sodium: a systematic review and external evaluation in a Chinese sample of renal transplant recipients [PDF]

Frontiers in Pharmacology
BackgroundImmunosuppressive therapy remains the primary method for preventing rejection in renal transplant recipients. While multiple population pharmacokinetic (popPK) models of mycophenolate sodium (MPS) have been developed for this population, their ...
Tong Gao, Wen Xu, Xiao Li, Qie Guo, Donghua Liu, Xiaolei Zhang, Ping Leng, Jialin Sun   +7 more
doaj   +2 more sources

External Evaluation of Vancomycin Population Pharmacokinetic Models at Two Clinical Centers [PDF]

Frontiers in Pharmacology, 2021
Background: Numerous vancomycin population pharmacokinetic models in neonates have been published; however, their predictive performances remain unknown.
Yi-Xi Liu, Yi-Xi Liu, Haini Wen, Wan-Jie Niu, Jing-Jing Li, Zhi-Ling Li, Zheng Jiao   +6 more
doaj   +2 more sources

Bridging Literature and Real-World Evidence: External Evaluation and Development of Fluoxetine Population Pharmacokinetics Model [PDF]

Pharmaceutics
Background: Fluoxetine is widely prescribed to treat depression but exhibits high inter-individual and inter-ethnic pharmacokinetic (PK) variability. Most published population pharmacokinetic (PopPK) models were derived from Western patients, and their ...
Bing Han, Nuo Xu, Chen Ma, Gehang Ju, Xie Xi, Cheng Qian, Nan Guo, Xin Liu, Xiao Zhu, Cong Li, Li Liu   +10 more
doaj   +2 more sources

External Evaluation of Population Pharmacokinetic Models and Bayes-Based Dosing of Infliximab [PDF]

Pharmaceutics, 2021
Despite the well-demonstrated efficacy of infliximab in inflammatory diseases, treatment failure remains frequent. Dose adjustment using Bayesian methods has shown in silico its interest in achieving target plasma concentrations.
Celine Konecki, Catherine Feliu, Yoann Cazaubon, Delphine Giusti, Marcelle Tonye-Libyh, Hedia Brixi, Guillaume Cadiot, Amélie Biron, Zoubir Djerada   +8 more
doaj   +2 more sources

Psychological Distress of High School Graduates During Social Distancing in Croatia

European Journal of Mental Health, 2022
Introduction: The COVID-19 pandemic has influenced the whole world, thus also affecting the high school graduates in Croatia. Aims: The purpose of the study was to examine the psychological distress high school graduates experienced during the COVID-19 ...
Natalija ĆURKOVIĆ, Jelena BUGARIN, Lorelaj LUKACIN   +2 more
doaj   +5 more sources