Results 161 to 170 of about 1,020,393 (303)

External Evaluation of Population Pharmacokinetic Models of Methotrexate for Model-Informed Precision Dosing in Pediatric Patients with Acute Lymphoid Leukemia. [PDF]

Pharmaceutics, 2023
Wang S, Yin Q, Yang M, Cheng Z, Xie F.
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

External Evaluation of Risperidone Population Pharmacokinetic Models Using Opportunistic Pediatric Data. [PDF]

Front Pharmacol, 2022
Karatza E, Ganguly S, Hornik CD, Muller WJ, Al-Uzri A, James L, Balevic SJ, Gonzalez D.   +7 more
europepmc   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

CRP-Commissioned External Evaluation of Dryland Systems INTERIM REPORT

, 2016
CRP-Commissioned External Evaluation of Dryland Systems_INTERIM ...
Merrey, Doughlas
core  

Prospective and external evaluation of an AI model for continuous and early prediction of moderate and severe AKI in critically ill patients. [PDF]

Intensive Care Med Exp
Alfieri F, Zappalà S, Bacci A, Cauda V, Basso M, Musso G, Cochelli L, Votta CD, Mariconti L, Maderna L, Russo G, Gomez J, Esteban-Reboll F, Gilavert Cuevas MC, Bodì M, Finazzi S, Kashani K, Ancona A.   +17 more
europepmc   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

External Evaluation of a Plasma and Cerebrospinal Fluid Population Pharmacokinetics Model of Meropenem in Infants. [PDF]

J Pediatr Pharmacol Ther
Boutzoukas AE, Ngo NB, Balevic S, Hornik CD, Berkovitch M, James LP, Kohn E, Anderson SG, Turdalieva S, Payne EH, Hope W, Lutsar I, Benjamin DK, Greenberg RG.   +13 more
europepmc   +1 more source

Joint External Evaluation scores and communicable disease deaths: An ecological study on the difference between epidemics and pandemics. [PDF]

PLOS Glob Public Health, 2022
Jain V, Sharp A, Neilson M, Bausch DG, Beaney T.   +4 more
europepmc   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source